Persimmon-derived tannin has bacteriostatic and anti-inflammatory activity in a murine model of Mycobacterium avium complex (MAC) disease

Nontuberculous mycobacteria (NTM), including Mycobacterium avium complex (MAC), cause opportunistic chronic pulmonary infections. Notably, MAC susceptibility is regulated by various factors, including the host immune system. Persimmon (Ebenaceae Diospyros kaki Thunb.) tannin is a condensed tannin co...

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Veröffentlicht in:	PloS one 2017-08, Vol.12 (8), p.e0183489-e0183489
Hauptverfasser:	Matsumura, Yoko, Kitabatake, Masahiro, Ouji-Sageshima, Noriko, Yasui, Satsuki, Mochida, Naoko, Nakano, Ryuichi, Kasahara, Kei, Tomoda, Koichi, Yano, Hisakazu, Kayano, Shin-Ichi, Ito, Toshihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorbance Animal models Animals Anti-Bacterial Agents - therapeutic use Anti-inflammatory agents Antioxidants Bacteria Bacteriostats Biology and Life Sciences Bone marrow Care and treatment Catechin Cytokines Diet Diospyros - chemistry Diospyros kaki Disease Models, Animal Female Fermented food Fruits Genetic aspects Granuloma Granulomas Health aspects Hydrologic data Immune system Immunology In vitro methods and tests In vivo methods and tests Infections Infectious diseases Inflammation Inflammation - drug therapy Lungs Macrophages Medicine and Health Sciences Mice Mice, Inbred BALB C Mycobacterium avium complex Mycobacterium avium-intracellulare Infection - drug therapy Nitric oxide Nitric-oxide synthase Nutrition Oxygen Pathogenesis Persimmons Physiological aspects Polymers Powder Research and analysis methods Rodents Stimulation Studies Tannic acid Tannins Tannins - therapeutic use Tumor necrosis factor-TNF
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