Diffusion tensor imaging profiles reveal specific neural tract distortion in normal pressure hydrocephalus

The pathogenesis of normal pressure hydrocephalus (NPH) remains unclear which limits both early diagnosis and prognostication. The responsiveness to intervention of differing, complex and concurrent injury patterns on imaging have not been well-characterized. We used diffusion tensor imaging (DTI) t...

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Veröffentlicht in:	PloS one 2017-08, Vol.12 (8), p.e0181624-e0181624
Hauptverfasser:	Keong, Nicole C, Pena, Alonso, Price, Stephen J, Czosnyka, Marek, Czosnyka, Zofia, DeVito, Elise E, Housden, Charlotte R, Sahakian, Barbara J, Pickard, John D
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Aged, 80 and over Alzheimer's disease Anisotropy Biology and Life Sciences Biomarkers Brain research Case-Control Studies Cerebrospinal fluid Compression Dementia Development and progression Diagnosis Diffusion Diffusion Tensor Imaging - methods Edema Female Fluids Humans Hydrocephalus Hydrocephalus, Normal Pressure - diagnosis Hydrocephalus, Normal Pressure - pathology Hydrocephalus, Normal Pressure - surgery Image Processing, Computer-Assisted Imaging Injuries Intervention Isotropy Magnetic resonance imaging Male Medicine and Health Sciences Methods Middle Aged Neural Pathways - pathology Neuroimaging Neuropathology Neuropsychological Tests Neurosciences Neurosurgery Normal pressure hydrocephalus Normality Older people Pathogenesis Patients Pediatrics Physical Sciences Pressure Psychiatry Research and Analysis Methods Substantia alba Topography White Matter - pathology
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