Assessment of physicians' awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?
The scarcity of familial hypercholesterolemia (FH) cases reported in Saudi Arabia might be indicative of a lack of awareness of this common genetic disease among physicians. To assess physicians' awareness, practice, and knowledge of FH in Saudi Arabia. This is a cross-sectional study conducted...
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description | The scarcity of familial hypercholesterolemia (FH) cases reported in Saudi Arabia might be indicative of a lack of awareness of this common genetic disease among physicians.
To assess physicians' awareness, practice, and knowledge of FH in Saudi Arabia.
This is a cross-sectional study conducted among physicians at four tertiary hospitals in Riyadh, Saudi Arabia between March 2016 and May 2016 using a self-administered questionnaire.
A total of 294 physicians completed the survey (response rate 90.1%). Overall, 92.9% of the participants have poor knowledge of FH while only 7.1% have acceptable knowledge. The majority (68.7%) of physicians rated their familiarity with FH as average or above average, and these had higher mean knowledge scores than participants with self-reported below average familiarity (mean 3.4 versus 2.6) (P < 0.001). Consultant physicians were 4.2 times more likely to be familiar with FH than residents or registrars (OR = 4.2, 95% CI = 1.9-9.1, P < 0.001). Physicians who currently managed FH patients had higher mean knowledge scores compared to those without FH patients in their care (3.5 versus 2.9) (P = 0.006). In addition, there were statistically significant differences between physicians' mean knowledge scores and their ages, levels of training, and years in practice. Moreover, a substantial deficit was identified in the awareness of various clinical algorithms to diagnose patients with FH, cascade screening, specialist lipid services, and the existence of statin alternatives, such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors.
A substantial deficit was found in the awareness, knowledge, practice, and detection of FH among physicians in Saudi Arabia. Extensive educational programs are required to raise physician awareness and implement best practices; only then can the impact of these interventions on FH management and patient outcome be assessed. |
doi_str_mv | 10.1371/journal.pone.0183494 |
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To assess physicians' awareness, practice, and knowledge of FH in Saudi Arabia.
This is a cross-sectional study conducted among physicians at four tertiary hospitals in Riyadh, Saudi Arabia between March 2016 and May 2016 using a self-administered questionnaire.
A total of 294 physicians completed the survey (response rate 90.1%). Overall, 92.9% of the participants have poor knowledge of FH while only 7.1% have acceptable knowledge. The majority (68.7%) of physicians rated their familiarity with FH as average or above average, and these had higher mean knowledge scores than participants with self-reported below average familiarity (mean 3.4 versus 2.6) (P < 0.001). Consultant physicians were 4.2 times more likely to be familiar with FH than residents or registrars (OR = 4.2, 95% CI = 1.9-9.1, P < 0.001). Physicians who currently managed FH patients had higher mean knowledge scores compared to those without FH patients in their care (3.5 versus 2.9) (P = 0.006). In addition, there were statistically significant differences between physicians' mean knowledge scores and their ages, levels of training, and years in practice. Moreover, a substantial deficit was identified in the awareness of various clinical algorithms to diagnose patients with FH, cascade screening, specialist lipid services, and the existence of statin alternatives, such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors.
A substantial deficit was found in the awareness, knowledge, practice, and detection of FH among physicians in Saudi Arabia. Extensive educational programs are required to raise physician awareness and implement best practices; only then can the impact of these interventions on FH management and patient outcome be assessed.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0183494</identifier><identifier>PMID: 28817709</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adult ; Age ; Algorithms ; Analysis ; Atherosclerosis ; Awareness ; Beliefs, opinions and attitudes ; Cardiovascular disease ; Cross-Sectional Studies ; Data collection ; Education ; Familiarity ; Family physicians ; Female ; Genetic aspects ; Health Knowledge, Attitudes, Practice ; Heart ; Humans ; Hypercholesterolemia ; Hyperlipoproteinemia Type II - diagnosis ; Hyperlipoproteinemia Type II - therapy ; Internal medicine ; Kexin ; Knowledge ; Lipids ; Lipoproteins ; Male ; Medical diagnosis ; Medical personnel ; Medical screening ; Medicine ; Medicine and Health Sciences ; Middle Aged ; Mortality ; Mutation ; Patients ; People and Places ; Physicians ; Practice ; Primary care ; Proprotein convertases ; Questionnaires ; Review boards ; Saudi Arabia ; Statistical analysis ; Subtilisin ; Training</subject><ispartof>PloS one, 2017-08, Vol.12 (8), p.e0183494-e0183494</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Batais et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Batais et al 2017 Batais et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-e98284b080315e60a24b5752b9b4291fb93e066953d254d526ce3b94c0f6ef743</citedby><cites>FETCH-LOGICAL-c692t-e98284b080315e60a24b5752b9b4291fb93e066953d254d526ce3b94c0f6ef743</cites><orcidid>0000-0001-6766-7553</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560711/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560711/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28817709$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>van Wouwe, Jacobus P.</contributor><creatorcontrib>Batais, Mohammed Ali</creatorcontrib><creatorcontrib>Almigbal, Turky H</creatorcontrib><creatorcontrib>Bin Abdulhak, Aref A</creatorcontrib><creatorcontrib>Altaradi, Hani B</creatorcontrib><creatorcontrib>AlHabib, Khalid F</creatorcontrib><title>Assessment of physicians' awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The scarcity of familial hypercholesterolemia (FH) cases reported in Saudi Arabia might be indicative of a lack of awareness of this common genetic disease among physicians.
To assess physicians' awareness, practice, and knowledge of FH in Saudi Arabia.
This is a cross-sectional study conducted among physicians at four tertiary hospitals in Riyadh, Saudi Arabia between March 2016 and May 2016 using a self-administered questionnaire.
A total of 294 physicians completed the survey (response rate 90.1%). Overall, 92.9% of the participants have poor knowledge of FH while only 7.1% have acceptable knowledge. The majority (68.7%) of physicians rated their familiarity with FH as average or above average, and these had higher mean knowledge scores than participants with self-reported below average familiarity (mean 3.4 versus 2.6) (P < 0.001). Consultant physicians were 4.2 times more likely to be familiar with FH than residents or registrars (OR = 4.2, 95% CI = 1.9-9.1, P < 0.001). Physicians who currently managed FH patients had higher mean knowledge scores compared to those without FH patients in their care (3.5 versus 2.9) (P = 0.006). In addition, there were statistically significant differences between physicians' mean knowledge scores and their ages, levels of training, and years in practice. Moreover, a substantial deficit was identified in the awareness of various clinical algorithms to diagnose patients with FH, cascade screening, specialist lipid services, and the existence of statin alternatives, such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors.
A substantial deficit was found in the awareness, knowledge, practice, and detection of FH among physicians in Saudi Arabia. Extensive educational programs are required to raise physician awareness and implement best practices; only then can the impact of these interventions on FH management and patient outcome be assessed.</description><subject>Adult</subject><subject>Age</subject><subject>Algorithms</subject><subject>Analysis</subject><subject>Atherosclerosis</subject><subject>Awareness</subject><subject>Beliefs, opinions and attitudes</subject><subject>Cardiovascular disease</subject><subject>Cross-Sectional Studies</subject><subject>Data collection</subject><subject>Education</subject><subject>Familiarity</subject><subject>Family physicians</subject><subject>Female</subject><subject>Genetic aspects</subject><subject>Health Knowledge, Attitudes, Practice</subject><subject>Heart</subject><subject>Humans</subject><subject>Hypercholesterolemia</subject><subject>Hyperlipoproteinemia Type II - diagnosis</subject><subject>Hyperlipoproteinemia Type II - therapy</subject><subject>Internal medicine</subject><subject>Kexin</subject><subject>Knowledge</subject><subject>Lipids</subject><subject>Lipoproteins</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical personnel</subject><subject>Medical screening</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Mutation</subject><subject>Patients</subject><subject>People and Places</subject><subject>Physicians</subject><subject>Practice</subject><subject>Primary care</subject><subject>Proprotein convertases</subject><subject>Questionnaires</subject><subject>Review boards</subject><subject>Saudi Arabia</subject><subject>Statistical analysis</subject><subject>Subtilisin</subject><subject>Training</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk11v0zAUhiMEYmPwDxBYmsTHRYu_YsdcgKqJj0qTJjHg1jpJnMbDiYudMPrvcWk2tWgX2Be27Oe8x37tk2VPCZ4TJsmbKz-GHtx87Xszx6RgXPF72TFRjM4Exez-3vwoexTjFcY5K4R4mB3RoiBSYnWcxUWMJsbO9APyDVq3m2grC318ieAagunTJoK-Rj96f-1MvTJbrIHOOgsOtZu1CVXrnYmDCWnoLCDbo0sYa4sWAUoLb9EyoqE1wSBAK1i_f5w9aMBF82QaT7JvHz98Pfs8O7_4tDxbnM8qoegwM6qgBS9xgRnJjcBAeZnLnJaq5FSRplTMYCFUzmqa8zqnojKsVLzCjTCN5Owke77TXTsf9eRX1MkVzDmRdEssd0Tt4Uqvg-0gbLQHq_8u-LDSEAZbOaMbTCFnMjUhuQJaSCY5AUkLpUgBImm9m7KNZWfqKjkawB2IHu70ttUr_0vnucCSkCTwahII_ueYDNWdjZVxDnrjx-ncBSb5NtfpP-jdt5uoFaQL2L7xKW-1FdWLHBMpcMqaqPkdVOp1eswqfa7GpvWDgNcHAYkZzO9hBWOMenn55f_Zi--H7Is9tjXghjZ6Nw7W9_EQ5DuwCj7GYJpbkwnW29q4cUNva0NPtZHCnu0_0G3QTTGwP9lUByQ</recordid><startdate>20170817</startdate><enddate>20170817</enddate><creator>Batais, 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of physicians' awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?</title><author>Batais, Mohammed Ali ; Almigbal, Turky H ; Bin Abdulhak, Aref A ; Altaradi, Hani B ; AlHabib, Khalid F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-e98284b080315e60a24b5752b9b4291fb93e066953d254d526ce3b94c0f6ef743</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Age</topic><topic>Algorithms</topic><topic>Analysis</topic><topic>Atherosclerosis</topic><topic>Awareness</topic><topic>Beliefs, opinions and attitudes</topic><topic>Cardiovascular disease</topic><topic>Cross-Sectional Studies</topic><topic>Data collection</topic><topic>Education</topic><topic>Familiarity</topic><topic>Family physicians</topic><topic>Female</topic><topic>Genetic aspects</topic><topic>Health Knowledge, Attitudes, 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analysis</topic><topic>Subtilisin</topic><topic>Training</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Batais, Mohammed Ali</creatorcontrib><creatorcontrib>Almigbal, Turky H</creatorcontrib><creatorcontrib>Bin Abdulhak, Aref A</creatorcontrib><creatorcontrib>Altaradi, Hani B</creatorcontrib><creatorcontrib>AlHabib, Khalid F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health 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Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Batais, Mohammed Ali</au><au>Almigbal, Turky H</au><au>Bin Abdulhak, Aref A</au><au>Altaradi, Hani B</au><au>AlHabib, Khalid F</au><au>van Wouwe, Jacobus P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of physicians' awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap?</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-08-17</date><risdate>2017</risdate><volume>12</volume><issue>8</issue><spage>e0183494</spage><epage>e0183494</epage><pages>e0183494-e0183494</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The scarcity of familial hypercholesterolemia (FH) cases reported in Saudi Arabia might be indicative of a lack of awareness of this common genetic disease among physicians.
To assess physicians' awareness, practice, and knowledge of FH in Saudi Arabia.
This is a cross-sectional study conducted among physicians at four tertiary hospitals in Riyadh, Saudi Arabia between March 2016 and May 2016 using a self-administered questionnaire.
A total of 294 physicians completed the survey (response rate 90.1%). Overall, 92.9% of the participants have poor knowledge of FH while only 7.1% have acceptable knowledge. The majority (68.7%) of physicians rated their familiarity with FH as average or above average, and these had higher mean knowledge scores than participants with self-reported below average familiarity (mean 3.4 versus 2.6) (P < 0.001). Consultant physicians were 4.2 times more likely to be familiar with FH than residents or registrars (OR = 4.2, 95% CI = 1.9-9.1, P < 0.001). Physicians who currently managed FH patients had higher mean knowledge scores compared to those without FH patients in their care (3.5 versus 2.9) (P = 0.006). In addition, there were statistically significant differences between physicians' mean knowledge scores and their ages, levels of training, and years in practice. Moreover, a substantial deficit was identified in the awareness of various clinical algorithms to diagnose patients with FH, cascade screening, specialist lipid services, and the existence of statin alternatives, such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors.
A substantial deficit was found in the awareness, knowledge, practice, and detection of FH among physicians in Saudi Arabia. Extensive educational programs are required to raise physician awareness and implement best practices; only then can the impact of these interventions on FH management and patient outcome be assessed.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28817709</pmid><doi>10.1371/journal.pone.0183494</doi><tpages>e0183494</tpages><orcidid>https://orcid.org/0000-0001-6766-7553</orcidid><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
subjects | Adult Age Algorithms Analysis Atherosclerosis Awareness Beliefs, opinions and attitudes Cardiovascular disease Cross-Sectional Studies Data collection Education Familiarity Family physicians Female Genetic aspects Health Knowledge, Attitudes, Practice Heart Humans Hypercholesterolemia Hyperlipoproteinemia Type II - diagnosis Hyperlipoproteinemia Type II - therapy Internal medicine Kexin Knowledge Lipids Lipoproteins Male Medical diagnosis Medical personnel Medical screening Medicine Medicine and Health Sciences Middle Aged Mortality Mutation Patients People and Places Physicians Practice Primary care Proprotein convertases Questionnaires Review boards Saudi Arabia Statistical analysis Subtilisin Training |
title | Assessment of physicians' awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: Is there a gap? |
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