Recurrently connected and localized neuronal communities initiate coordinated spontaneous activity in neuronal networks

Developing neuronal systems intrinsically generate coordinated spontaneous activity that propagates by involving a large number of synchronously firing neurons. In vivo, waves of spikes transiently characterize the activity of developing brain circuits and are fundamental for activity-dependent circ...

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Veröffentlicht in:	PLoS computational biology 2017-07, Vol.13 (7), p.e1005672-e1005672
Hauptverfasser:	Lonardoni, Davide, Amin, Hayder, Di Marco, Stefano, Maccione, Alessandro, Berdondini, Luca, Nieus, Thierry
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - physiology Animals Authorship Biology and Life Sciences Brain Brain research Bursts Cell culture Cells, Cultured Circuits Communities Computation Computational Biology Computational neuroscience Computer and Information Sciences Computer simulation Firing pattern High resolution Hippocampus - cytology In vitro methods and tests Medicine and Health Sciences Models, Neurological N-Methyl-D-aspartic acid Nerve Net - cytology Nerve Net - physiology Neural circuitry Neural networks Neurons Neurons - cytology Neurons - physiology Neurosciences Physiological aspects Rats Research and Analysis Methods Spikes Spiking Studies α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid γ-Aminobutyric acid
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