Double impact: natural molluscicide for schistosomiasis vector control also impedes development of Schistosoma mansoni cercariae into adult parasites

Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly the parasite's bio...

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Veröffentlicht in:	PLoS neglected tropical diseases 2017-07, Vol.11 (7), p.e0005789
Hauptverfasser:	Augusto, Ronaldo de Carvalho, Tetreau, Guillaume, Chan, Philippe, Walet-Balieu, Marie-Laure, Mello-Silva, Clélia Christina, Santos, Claudia Portes, Grunau, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biology Biology and Life Sciences Biomphalaria - parasitology Brazil Cercaria - drug effects Cercaria - growth & development Control Countries Disease transmission Drugs Electron microscopy Energy Energy metabolism Female Females Fitness Fresh water Freshwater environments Funding Genomics Granulomas Health aspects Hosts Impact damage Infections Latex Latex - administration & dosage Life cycle Life cycle engineering Life cycles Life Sciences Linear Models Liver - pathology Male Medicine and Health Sciences Metabolic pathways Metabolism Mice Microbiology and Parasitology Microscopy, Electron Molluscacides - administration & dosage Molluscicides Mollusks Morphology Organizations Parasite Load Parasites Parasitic diseases Parasitology Pathways Pest control Pests Phenotypes Physical Sciences Physiological aspects Physiology Plant Extracts - administration & dosage Praziquantel Proteomics Public health Schistosoma mansoni - drug effects Schistosoma mansoni - ultrastructure Schistosomiasis Schistosomiasis mansoni - parasitology Schistosomiasis mansoni - prevention & control Sequence Analysis, RNA Side effects Snails Software Stem cells Toxicity Transmission Trends Tropical diseases Vulnerability
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