A Drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure

The genetic factors that give rise to variation in susceptibility to environmental toxins remain largely unexplored. Studies on genetic variation in susceptibility to environmental toxins are challenging in human populations, due to the variety of clinical symptoms and difficulty in determining whic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS genetics 2017-07, Vol.13 (7), p.e1006907
Hauptverfasser:	Zhou, Shanshan, Luoma, Sarah E, St Armour, Genevieve E, Thakkar, Esha, Mackay, Trudy F C, Anholt, Robert R H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioinformatics Biology and Life Sciences Cadmium Computer and Information Sciences Deoxyribonucleic acid DNA DNA methylation Drosophila Drosophila melanogaster - drug effects Drosophila melanogaster - genetics Drug Resistance - genetics Ecological risk assessment Exposure Female Gene expression Gene mapping Genetic aspects Genetic diversity Genetic factors Genetic Predisposition to Disease Genetic variation Genome-Wide Association Study Genomes Genomics Health aspects Heavy metals Humans Insects Male Medicine and Health Sciences Metals, Heavy - toxicity Mutation Parameter estimation Physical Sciences Physiology Polymorphism, Single Nucleotide - genetics Population genetics Quantitative genetics Quantitative trait loci Quantitative Trait Loci - genetics Research and Analysis Methods RNA-mediated interference Sex Characteristics Single-nucleotide polymorphism Statistical analysis Studies Time lag Toxicants Toxicity Toxicogenetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!