How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

The specific phenotype of mature differentiated beta cells not only depends on the specific presence of genes that allow beta cell function but also on the selective absence of housekeeping genes ("disallowed genes") that would interfere with this function. Recent studies have shown that b...

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Veröffentlicht in:PloS one 2017-08, Vol.12 (8), p.e0181651-e0181651
Hauptverfasser: Lemaire, Katleen, Granvik, Mikaela, Schraenen, Anica, Goyvaerts, Lotte, Van Lommel, Leentje, Gómez-Ruiz, Ana, In 't Veld, Peter, Gilon, Patrick, Schuit, Frans
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Sprache:eng
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