Apolipoprotein A-I exchange is impaired in metabolic syndrome patients asymptomatic for diabetes and cardiovascular disease

We tested the hypothesis that HDL-apolipoprotein A-I exchange (HAE), a measure of high-density lipoprotein (HDL) function and a key step in reverse cholesterol transport (RCT), is impaired in metabolic syndrome (MetSyn) patients who are asymptomatic for diabetes and cardiovascular disease. We also c...

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Veröffentlicht in:	PloS one 2017-08, Vol.12 (8), p.e0182217-e0182217
Hauptverfasser:	Borja, Mark S, Hammerson, Bradley, Tang, Chongren, Savinova, Olga V, Shearer, Gregory C, Oda, Michael N
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCA1 protein Adult Apolipoprotein A Apolipoprotein A-I Apolipoprotein A-I - metabolism Apolipoproteins ATP Binding Cassette Transporter 1 ATP-binding protein Biology and Life Sciences Biosynthesis Cardiovascular disease Cardiovascular diseases Cholesterol Cholesterol - blood Coronary vessels Correlation Diabetes Diabetes mellitus Efflux Exchanging Female HDL cholesterol Health risks High density lipoprotein Hospitals Humans Lipids Lipoproteins, HDL - blood Low density lipoprotein Male Medical research Medicine Medicine and Health Sciences Metabolic disorders Metabolic syndrome Metabolic Syndrome - metabolism Metabolic syndrome X Middle Aged Patients Physical Sciences Populations Protein Transport Proteins Regression analysis Research and Analysis Methods Risk Risk factors
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