Glutamate/GABA+ ratio is associated with the psychosocial domain of autistic and schizotypal traits

The autism and schizophrenia spectra overlap to a large degree in the social and interpersonal domains. Similarly, abnormal excitatory glutamate and inhibitory γ-aminobutyric acid (GABA) neurotransmitter concentrations have been reported for both spectra, with the interplay of these neurotransmitter...

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Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0181961-e0181961
Hauptverfasser:	Ford, Talitha C, Nibbs, Richard, Crewther, David P
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Acids Adolescent Adult Adults Anxieties Anxiety Attention Autism Autistic Disorder - pathology Autistic Disorder - psychology Behavior Biology and Life Sciences Brain Cognition & reasoning Communication Constrictions Cortex Excitation spectra Female gamma-Aminobutyric Acid - analysis Genotype & phenotype Glutamic acid Glutamic Acid - analysis Humans Inhibition (psychology) Magnetic resonance Magnetic resonance spectroscopy Male Medicine Medicine and Health Sciences Mental disorders Mental task performance Neurotransmitter Agents - analysis Neurotransmitters NMR Nuclear magnetic resonance Personality Personality Tests Phenotype Proton magnetic resonance Proton Magnetic Resonance Spectroscopy Psychiatric Status Rating Scales Psychological aspects Psychopharmacology Schizophrenia Schizotypal Personality Disorder - pathology Schizotypal Personality Disorder - psychology Skills Social Sciences Social skills Spectroscopic analysis Spectroscopy Spectrum analysis Speech Studies Surveys and Questionnaires Switching Young Adult γ-Aminobutyric acid
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