The effect of disease and respiration on airway shape in patients with moderate persistent asthma

Computational models of gas transport and aerosol deposition frequently utilize idealized models of bronchial tree structure, where airways are considered a network of bifurcating cylinders. However, changes in the shape of the lung during respiration affect the geometry of the airways, especially i...

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Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0182052-e0182052
Hauptverfasser:	Montesantos, Spyridon, Katz, Ira, Venegas, Jose, Pichelin, Marine, Caillibotte, Georges
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Aerosol deposition Airway management Asthma Asthma - diagnostic imaging Asthma - physiopathology Bifurcations Biology and Life Sciences Bronchi Bronchus Care and treatment Case-Control Studies CAT scans Computed tomography Computer applications Constrictions Cylinders Diagnosis Disease Female Gas transport High resolution Humans Image acquisition Image resolution Lobes Lung - diagnostic imaging Lung - physiology Lung Volume Measurements Lungs Male Mathematical models Medical imaging Medicine and Health Sciences Methacholine Patients Physical Sciences R&D Research & development Research and Analysis Methods Respiration Respiratory tract Respiratory tract diseases Tomography, X-Ray Computed Transportation models Variability Young Adult
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