Vibrio vulnificus induces mTOR activation and inflammatory responses in macrophages

Vibrio vulnificus (V. vulnificus), a Gram-negative marine bacterium, can cause life-threatening primary septicemia, especially in patients with liver diseases. How V. vulnificus affects the liver and how it acts on macrophages are not well understood. In this report, we demonstrated that V. vulnific...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0181454-e0181454
Hauptverfasser:	Xie, Dan-Li, Zheng, Meng-Meng, Zheng, Yi, Gao, Hui, Zhang, Jie, Zhang, Ting, Guo, Jian-Chun, Yang, X Frank, Zhong, Xiao-Ping, Lou, Yong-Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Bacteria Bacterial infections Biology and Life Sciences Cell activation Cytokines Damage Education Enzyme Activation Fish Gangrene Health aspects Hepatitis Hepatology Immunology Infections Inflammation Inflammation - microbiology Inflammatory response Inhibition Kupffer Cells - cytology Laboratories Liver Liver - immunology Liver cirrhosis Liver diseases Macrophages Macrophages - metabolism Macrophages - microbiology Medicine Medicine and Health Sciences Metabolism Mice Mice, Inbred C57BL Neutrophils - cytology NF-kappa B - metabolism Pathogens Patients Risk factors Septicemia Signal transduction Survival analysis TOR protein TOR Serine-Threonine Kinases - metabolism Vibrio Vibrio Infections - complications Vibrio vulnificus - physiology Waterborne diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!