Cryptococcal meningitis: A neglected NTD?
Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation. Of these OIs, cryptococcal meningitis, a dea...
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| Veröffentlicht in: | PLoS neglected tropical diseases 2017-06, Vol.11 (6), p.e0005575-e0005575 |
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| creator | Molloy, Síle F Chiller, Tom Greene, Gregory S Burry, Jessica Govender, Nelesh P Kanyama, Cecilia Mfinanga, Sayoki Lesikari, Sokoine Mapoure, Yacouba N Kouanfack, Charles Sini, Victor Temfack, Elvis Boulware, David R Dromer, Francoise Denning, David W Day, Jeremy Stone, Neil R H Bicanic, Tihana Jarvis, Joseph N Lortholary, Olivier Harrison, Thomas S Jaffar, Shabbar Loyse, Angela |
| description | Although HIV/AIDS has been anything but neglected over the last decade, opportunistic infections (OIs) are increasingly overlooked as large-scale donors shift their focus from acute care to prevention and earlier antiretroviral treatment (ART) initiation. Of these OIs, cryptococcal meningitis, a deadly invasive fungal infection, continues to affect hundreds of thousands of HIV patients with advanced disease each year and is responsible for an estimated 15%–20% of all AIDS-related deaths [1, 2]. Yet cryptococcal meningitis ranks amongst the most poorly funded “neglected” diseases in the world, receiving 0.2% of available relevant research and development (R&D) funding, according to Policy Cures’ 2016 Global Funding of Innovation for Neglected Diseases (G-Finder) Report [3, 4]. |
| doi_str_mv | 10.1371/journal.pntd.0005575 |
| format | Article |
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Yet cryptococcal meningitis ranks amongst the most poorly funded “neglected” diseases in the world, receiving 0.2% of available relevant research and development (R&D) funding, according to Policy Cures’ 2016 Global Funding of Innovation for Neglected Diseases (G-Finder) Report [3, 4].</description><identifier>ISSN: 1935-2735</identifier><identifier>ISSN: 1935-2727</identifier><identifier>EISSN: 1935-2735</identifier><identifier>DOI: 10.1371/journal.pntd.0005575</identifier><identifier>PMID: 28662028</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Antifungal Agents - therapeutic use ; Biology and Life Sciences ; Biomedical Research ; Cryptococcal meningitis ; Diagnosis ; Diseases ; Global Health ; Health aspects ; HIV patients ; HIV tests ; Human health and pathology ; Humans ; Infectious diseases ; Life Sciences ; Medicine and Health Sciences ; Meningitis ; Meningitis, Cryptococcal - epidemiology ; Meningitis, Cryptococcal - prevention & control ; Mortality ; Neglected Diseases ; People and Places ; Public health ; Tropical diseases ; Tropical Medicine ; Viewpoints</subject><ispartof>PLoS neglected tropical diseases, 2017-06, Vol.11 (6), p.e0005575-e0005575</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Public Library of Science. 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Yet cryptococcal meningitis ranks amongst the most poorly funded “neglected” diseases in the world, receiving 0.2% of available relevant research and development (R&D) funding, according to Policy Cures’ 2016 Global Funding of Innovation for Neglected Diseases (G-Finder) Report [3, 4].</description><subject>Antifungal Agents - therapeutic use</subject><subject>Biology and Life Sciences</subject><subject>Biomedical Research</subject><subject>Cryptococcal meningitis</subject><subject>Diagnosis</subject><subject>Diseases</subject><subject>Global Health</subject><subject>Health aspects</subject><subject>HIV patients</subject><subject>HIV tests</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Life Sciences</subject><subject>Medicine and Health Sciences</subject><subject>Meningitis</subject><subject>Meningitis, Cryptococcal - epidemiology</subject><subject>Meningitis, Cryptococcal - prevention & 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| subjects | Antifungal Agents - therapeutic use Biology and Life Sciences Biomedical Research Cryptococcal meningitis Diagnosis Diseases Global Health Health aspects HIV patients HIV tests Human health and pathology Humans Infectious diseases Life Sciences Medicine and Health Sciences Meningitis Meningitis, Cryptococcal - epidemiology Meningitis, Cryptococcal - prevention & control Mortality Neglected Diseases People and Places Public health Tropical diseases Tropical Medicine Viewpoints |
| title | Cryptococcal meningitis: A neglected NTD? |
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