Performance characteristics of finger-stick dried blood spots (DBS) on the determination of human immunodeficiency virus (HIV) treatment failure in a pediatric population in Mozambique

Quantitative plasma viral load (VL) at 1000 copies /mL was recommended as the threshold to confirm antiretroviral therapy (ART) failure by the World Health Organization (WHO). Because of ongoing challenges of using plasma for VL testing in resource-limited settings (RLS), especially for children, th...

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Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0181054-e0181054
Hauptverfasser:	Chang, Joy, de Sousa, Amina, Sabatier, Jennifer, Assane, Mariamo, Zhang, Guoqing, Bila, Dulce, Vaz, Paula, Alfredo, Charity, Cossa, Loide, Bhatt, Nilesh, Koumans, Emilia H, Yang, Chunfu, Rivadeneira, Emilia, Jani, Ilesh, Houston, James C
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adolescent AIDS Anti-Retroviral Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antiretroviral therapy Antiretroviral Therapy, Highly Active - methods Biology and Life Sciences Child Child, Preschool Children Cross-Sectional Studies Disease control Disease prevention Dried Blood Spot Testing - methods Drug resistance Drug therapy Failure Female HIV HIV Infections - drug therapy HIV Infections - virology HIV-1 - drug effects HIV-1 - physiology Human immunodeficiency virus Humans Infant Male Medical diagnosis Medicine and Health Sciences Monitoring Mozambique Pediatrics People and Places Phlebotomy Public health Sensitivity Sensitivity and Specificity Spots Treatment Failure Viral Load Viruses
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