Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects

Fatigue is the symptom most commonly reported by long-term cancer survivors and is increasingly recognized as related to skeletal muscle dysfunction. Traditional chemotherapeutic agents can cause acute toxicities including cardiac and skeletal myopathies. To investigate the mechanism by which chemot...

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Veröffentlicht in:PloS one 2017-07, Vol.12 (7), p.e0181086
Hauptverfasser: Crouch, Marie-Laure, Knowels, Gary, Stuppard, Rudolph, Ericson, Nolan G, Bielas, Jason H, Marcinek, David J, Syrjala, Karen L
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Sprache:eng
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