Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda

Introduction of GeneXpert MTB/RIF (Xpert) assay has constituted a major breakthrough for tuberculosis (TB) diagnostics. Several patient factors may influence diagnostic performance of Xpert including sputum quality. We carried out a prospective, observational, cross-sectional study to determine the...

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Veröffentlicht in:	PloS one 2017-07, Vol.12 (7), p.e0180572-e0180572
Hauptverfasser:	Meyer, Amanda J, Atuheire, Collins, Worodria, William, Kizito, Samuel, Katamba, Achilles, Sanyu, Ingvar, Andama, Alfred, Ayakaka, Irene, Cattamanchi, Adithya, Bwanga, Freddie, Huang, Laurence, Davis, J Lucian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Biology and Life Sciences Blood Collaboration Critical care Cross-Sectional Studies Demographics Diagnosis Diagnostic systems Epidemiology Female Fluorescence Fluorescence microscopy Health sciences HIV Hospitals Human immunodeficiency virus Humans Infectious diseases Laboratories Lung diseases Male Medical diagnosis Medicine Medicine and Health Sciences Microscopy Molecular Diagnostic Techniques Multivariate analysis Mycobacterium tuberculosis - pathogenicity Patients People and Places Physical Sciences Pneumonia Prospective Studies Public health Quality Sensitivity Smear Sputum Sputum - microbiology Sputum culture Studies Tuberculosis Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - epidemiology Tuberculosis, Pulmonary - microbiology Tuberculosis, Pulmonary - pathology Uganda Young Adult
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