Caspase-6 mediates resistance against Burkholderia pseudomallei infection and influences the expression of detrimental cytokines

Caspase-6 is a member of the executioner caspases and known to play a role in innate and adaptive immune processes. However, its role in infectious diseases has rarely been addressed yet. We here examined the impact of caspase-6 in an in vivo infection model using the Gram-negative rod Burkholderia...

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Veröffentlicht in:PloS one 2017-07, Vol.12 (7), p.e0180203-e0180203
Hauptverfasser: Bartel, Alexander, Göhler, André, Hopf, Verena, Breitbach, Katrin
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Sprache:eng
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