Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques

Infection with Zika virus (ZIKV) is associated with human congenital fetal anomalies. To model fetal outcomes in nonhuman primates, we administered Asian-lineage ZIKV subcutaneously to four pregnant rhesus macaques. While non-pregnant animals in a previous study contemporary with the current report...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PLoS pathogens 2017-05, Vol.13 (5), p.e1006378-e1006378
Hauptverfasser:	Nguyen, Sydney M, Antony, Kathleen M, Dudley, Dawn M, Kohn, Sarah, Simmons, Heather A, Wolfe, Bryce, Salamat, M Shahriar, Teixeira, Leandro B C, Wiepz, Gregory J, Thoong, Troy H, Aliota, Matthew T, Weiler, Andrea M, Barry, Gabrielle L, Weisgrau, Kim L, Vosler, Logan J, Mohns, Mariel S, Breitbach, Meghan E, Stewart, Laurel M, Rasheed, Mustafa N, Newman, Christina M, Graham, Michael E, Wieben, Oliver E, Turski, Patrick A, Johnson, Kevin M, Post, Jennifer, Hayes, Jennifer M, Schultz-Darken, Nancy, Schotzko, Michele L, Eudailey, Josh A, Permar, Sallie R, Rakasz, Eva G, Mohr, Emma L, Capuano, 3rd, Saverio, Tarantal, Alice F, Osorio, Jorge E, O'Connor, Shelby L, Friedrich, Thomas C, O'Connor, David H, Golos, Thaddeus G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic Fluid - virology Animals Anomalies Biology and life sciences Cesarean section Cytomegalovirus Decidua Decidua - pathology Decidua - virology Disease Models, Animal Disease transmission Diseases and pests Distribution Female Femur Fetal Development Fetus Fetuses Gestation Gynecology Health aspects Humans Infections Infectious Disease Transmission, Vertical Infiltration Laboratories Leukocytes (neutrophilic) Listeria Lung - pathology Lung - virology Macaca mulatta Medicine Medicine and Health Sciences Membranes Monkeys & apes Obstetrics Optic nerve Pathology Pediatrics Physiological aspects Placenta Placenta - pathology Placenta - virology Pregnancy Pregnancy Complications, Infectious Primates Research and Analysis Methods Retina Ribonucleic acid Risk analysis Risk factors RNA RNA, Viral - analysis Spleen - pathology Spleen - virology Therapeutic applications Tissues Ultrasonic imaging Ultrasound Umbilical Cord - pathology Umbilical Cord - virology Vaccines Vector-borne diseases Velocity Viremia Viruses Zika virus Zika Virus - physiology Zika Virus Infection - pathology Zika Virus Infection - transmission Zika Virus Infection - virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!