Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy
To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects w...
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| Veröffentlicht in: | PloS one 2017-06, Vol.12 (6), p.e0177318 |
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| creator | Evangelista, Morgana de Araújo Dias, Fernando Augusto Lavezzo Dourado Júnior, Mário Emílio Teixeira do Nascimento, George Carlos Sarmento, Antonio Gualdi, Lucien Peroni Aliverti, Andrea Resqueti, Vanessa Fregonezi, Guilherme Augusto de Freitas |
| description | To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects with Myotonic dystrophy type 1 (DM1) compared with healthy subjects.
Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy.
MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test.
MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory muscles. |
| doi_str_mv | 10.1371/journal.pone.0177318 |
| format | Article |
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Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy.
MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test.
MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory muscles.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0177318</identifier><identifier>PMID: 28594857</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adult ; Anthropometry ; Biology and Life Sciences ; Care and treatment ; Contraction ; Design ; Design analysis ; Diagnosis ; Disease control ; Dolphins & porpoises ; Dystrophy ; Electromyography ; Exhalation - physiology ; Female ; Humans ; Inhalation - physiology ; Lungs ; Male ; Medicine and Health Sciences ; Muscle Relaxation - physiology ; Muscle strength ; Muscle Strength - physiology ; Muscles ; Muscular dystrophy ; Myotonic dystrophy ; Myotonic Dystrophy - physiopathology ; Pressure ; Research and Analysis Methods ; Respiration ; Respiratory function ; Respiratory Function Tests ; Respiratory muscles ; Respiratory Muscles - physiopathology ; ROC Curve ; Sample Size ; Sensitivity ; Sensitivity analysis ; Studies ; Time Factors</subject><ispartof>PloS one, 2017-06, Vol.12 (6), p.e0177318</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Evangelista et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Evangelista et al 2017 Evangelista et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-245402eae1df92e956e49559b4db0b90b460a9d14cfa5c0d942898e8253d4a103</citedby><cites>FETCH-LOGICAL-c692t-245402eae1df92e956e49559b4db0b90b460a9d14cfa5c0d942898e8253d4a103</cites><orcidid>0000-0001-6391-5652</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464542/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464542/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79343,79344</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28594857$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Artero, Ruben</contributor><creatorcontrib>Evangelista, Morgana de Araújo</creatorcontrib><creatorcontrib>Dias, Fernando Augusto Lavezzo</creatorcontrib><creatorcontrib>Dourado Júnior, Mário Emílio Teixeira</creatorcontrib><creatorcontrib>do Nascimento, George Carlos</creatorcontrib><creatorcontrib>Sarmento, Antonio</creatorcontrib><creatorcontrib>Gualdi, Lucien Peroni</creatorcontrib><creatorcontrib>Aliverti, Andrea</creatorcontrib><creatorcontrib>Resqueti, Vanessa</creatorcontrib><creatorcontrib>Fregonezi, Guilherme Augusto de Freitas</creatorcontrib><title>Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects with Myotonic dystrophy type 1 (DM1) compared with healthy subjects.
Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy.
MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test.
MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory muscles.</description><subject>Adult</subject><subject>Anthropometry</subject><subject>Biology and Life Sciences</subject><subject>Care and treatment</subject><subject>Contraction</subject><subject>Design</subject><subject>Design analysis</subject><subject>Diagnosis</subject><subject>Disease control</subject><subject>Dolphins & porpoises</subject><subject>Dystrophy</subject><subject>Electromyography</subject><subject>Exhalation - physiology</subject><subject>Female</subject><subject>Humans</subject><subject>Inhalation - physiology</subject><subject>Lungs</subject><subject>Male</subject><subject>Medicine and Health Sciences</subject><subject>Muscle Relaxation - physiology</subject><subject>Muscle strength</subject><subject>Muscle Strength - physiology</subject><subject>Muscles</subject><subject>Muscular dystrophy</subject><subject>Myotonic dystrophy</subject><subject>Myotonic Dystrophy - physiopathology</subject><subject>Pressure</subject><subject>Research and Analysis Methods</subject><subject>Respiration</subject><subject>Respiratory function</subject><subject>Respiratory Function Tests</subject><subject>Respiratory muscles</subject><subject>Respiratory Muscles - physiopathology</subject><subject>ROC Curve</subject><subject>Sample Size</subject><subject>Sensitivity</subject><subject>Sensitivity analysis</subject><subject>Studies</subject><subject>Time Factors</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNqNk12P1CAUhhujcdfVf2C0iYnRixmBQgduTDYbPyZZ3cSveEcoPZ1h0sIs0In99zI73c3U7IXhAgLPeeG8h5NlzzGa42KB321c761q51tnYY7wYlFg_iA7xaIgs5Kg4uHR-iR7EsIGIVbwsnycnRDOBOVscZr9_uqssTsVzA5yFQKE0IGNuWtyD2FrvIrOD3nXB91CHqIHu4rrXNk6VzqanYlDbmz-ZXAxCem8HhLjtuvhafaoUW2AZ-N8lv38-OHHxefZ5dWn5cX55UyXgsQZoYwiAgpw3QgCgpVABWOionWFKoEqWiIlakx1o5hGtaCECw6csKKmCqPiLHt50N22LsjRlCCxQAvGCkHKRCwPRO3URm696ZQfpFNG3mw4v5LKR5Pyk0yLCqUXMMEUBVHzigtKaUlIASCAJa3342191UGtk1VetRPR6Yk1a7lyO8lomTIlSeDNKODddQ8hys4EDW2rLLj-5t2cpvIintBX_6D3ZzdSK5USMLZx6V69F5XnNBWZFqLcuzS_h0qjhs7o9IMak_YnAW8nAYmJ8CeuVB-CXH7_9v_s1a8p-_qIXYNq4zq4to_G2TAF6QHU3oXgobkzGSO5b4BbN-S-AeTYACnsxXGB7oJuf3zxF7KxARk</recordid><startdate>20170608</startdate><enddate>20170608</enddate><creator>Evangelista, Morgana de Araújo</creator><creator>Dias, Fernando Augusto Lavezzo</creator><creator>Dourado Júnior, Mário Emílio Teixeira</creator><creator>do Nascimento, George Carlos</creator><creator>Sarmento, Antonio</creator><creator>Gualdi, Lucien Peroni</creator><creator>Aliverti, Andrea</creator><creator>Resqueti, Vanessa</creator><creator>Fregonezi, Guilherme Augusto de Freitas</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0001-6391-5652</orcidid></search><sort><creationdate>20170608</creationdate><title>Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy</title><author>Evangelista, Morgana de Araújo ; Dias, Fernando Augusto Lavezzo ; Dourado Júnior, Mário Emílio Teixeira ; do Nascimento, George Carlos ; Sarmento, Antonio ; Gualdi, Lucien Peroni ; Aliverti, Andrea ; Resqueti, Vanessa ; Fregonezi, Guilherme Augusto de Freitas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-245402eae1df92e956e49559b4db0b90b460a9d14cfa5c0d942898e8253d4a103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Anthropometry</topic><topic>Biology and Life Sciences</topic><topic>Care and treatment</topic><topic>Contraction</topic><topic>Design</topic><topic>Design analysis</topic><topic>Diagnosis</topic><topic>Disease control</topic><topic>Dolphins & porpoises</topic><topic>Dystrophy</topic><topic>Electromyography</topic><topic>Exhalation - physiology</topic><topic>Female</topic><topic>Humans</topic><topic>Inhalation - physiology</topic><topic>Lungs</topic><topic>Male</topic><topic>Medicine and Health Sciences</topic><topic>Muscle Relaxation - physiology</topic><topic>Muscle strength</topic><topic>Muscle Strength - physiology</topic><topic>Muscles</topic><topic>Muscular dystrophy</topic><topic>Myotonic dystrophy</topic><topic>Myotonic Dystrophy - physiopathology</topic><topic>Pressure</topic><topic>Research and Analysis Methods</topic><topic>Respiration</topic><topic>Respiratory function</topic><topic>Respiratory Function Tests</topic><topic>Respiratory muscles</topic><topic>Respiratory Muscles - physiopathology</topic><topic>ROC Curve</topic><topic>Sample Size</topic><topic>Sensitivity</topic><topic>Sensitivity analysis</topic><topic>Studies</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Evangelista, Morgana de Araújo</creatorcontrib><creatorcontrib>Dias, Fernando Augusto Lavezzo</creatorcontrib><creatorcontrib>Dourado Júnior, Mário Emílio Teixeira</creatorcontrib><creatorcontrib>do Nascimento, George Carlos</creatorcontrib><creatorcontrib>Sarmento, Antonio</creatorcontrib><creatorcontrib>Gualdi, Lucien Peroni</creatorcontrib><creatorcontrib>Aliverti, Andrea</creatorcontrib><creatorcontrib>Resqueti, Vanessa</creatorcontrib><creatorcontrib>Fregonezi, Guilherme Augusto de Freitas</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Opposing Viewpoints in Context (Gale)</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Evangelista, Morgana de Araújo</au><au>Dias, Fernando Augusto Lavezzo</au><au>Dourado Júnior, Mário Emílio Teixeira</au><au>do Nascimento, George Carlos</au><au>Sarmento, Antonio</au><au>Gualdi, Lucien Peroni</au><au>Aliverti, Andrea</au><au>Resqueti, Vanessa</au><au>Fregonezi, Guilherme Augusto de Freitas</au><au>Artero, Ruben</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-06-08</date><risdate>2017</risdate><volume>12</volume><issue>6</issue><spage>e0177318</spage><pages>e0177318-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects with Myotonic dystrophy type 1 (DM1) compared with healthy subjects.
Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy.
MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test.
MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory muscles.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28594857</pmid><doi>10.1371/journal.pone.0177318</doi><tpages>e0177318</tpages><orcidid>https://orcid.org/0000-0001-6391-5652</orcidid><oa>free_for_read</oa></addata></record> |
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| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_1907553926 |
| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Adult Anthropometry Biology and Life Sciences Care and treatment Contraction Design Design analysis Diagnosis Disease control Dolphins & porpoises Dystrophy Electromyography Exhalation - physiology Female Humans Inhalation - physiology Lungs Male Medicine and Health Sciences Muscle Relaxation - physiology Muscle strength Muscle Strength - physiology Muscles Muscular dystrophy Myotonic dystrophy Myotonic Dystrophy - physiopathology Pressure Research and Analysis Methods Respiration Respiratory function Respiratory Function Tests Respiratory muscles Respiratory Muscles - physiopathology ROC Curve Sample Size Sensitivity Sensitivity analysis Studies Time Factors |
| title | Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T22%3A42%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Noninvasive%20assessment%20of%20respiratory%20muscle%20strength%20and%20activity%20in%20Myotonic%20dystrophy&rft.jtitle=PloS%20one&rft.au=Evangelista,%20Morgana%20de%20Ara%C3%BAjo&rft.date=2017-06-08&rft.volume=12&rft.issue=6&rft.spage=e0177318&rft.pages=e0177318-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0177318&rft_dat=%3Cgale_plos_%3EA494843960%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1907553926&rft_id=info:pmid/28594857&rft_galeid=A494843960&rft_doaj_id=oai_doaj_org_article_5c9b06e4595a4e9d8b894446223ee9e5&rfr_iscdi=true |