The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer

Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. The aims of this study were to examine the relationships between inflammatory biomarkers and the Patient Reported Outcome Measures (PROMs) of pain, appetite and fatigue; and to e...

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Veröffentlicht in:	PloS one 2017-05, Vol.12 (5), p.e0177620-e0177620
Hauptverfasser:	Paulsen, Ørnulf, Laird, Barry, Aass, Nina, Lea, Tor, Fayers, Peter, Kaasa, Stein, Klepstad, Pål
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Analgesics Analysis Appetite - physiology Biology and Life Sciences Biomarkers Biomarkers - metabolism Cancer Cancer therapies Cancer treatment Chronic fatigue syndrome Clinical trials Cognitive ability Complications and side effects Corticoids Corticosteroid drugs Corticosteroids Cytokines Cytokines - metabolism Dosage and administration Double-Blind Method Erythrocyte sedimentation rate Fatigue Fatigue - metabolism Fatigue - physiopathology Female Health aspects Humans IL-1β Inflammation Inflammation - metabolism Inflammation - physiopathology Inflammatory response Interferon Lung cancer Male Medical research Medicine Medicine and Health Sciences Middle Aged Multiple regression analysis Narcotics Neoplasms - metabolism Neoplasms - physiopathology Neurosciences Oncology Opioids Pain Pain - metabolism Palliative care Pancreatic cancer Patients Quality of Life Randomized Controlled Trials as Topic - methods Regression analysis Risk factors Rodents Science Surveys and Questionnaires TNF inhibitors Transforming growth factor-b1 Tumor necrosis factor-TNF
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