A Ca2+ channel differentially regulates Clathrin-mediated and activity-dependent bulk endocytosis

Clathrin-mediated endocytosis (CME) and activity-dependent bulk endocytosis (ADBE) are two predominant forms of synaptic vesicle (SV) endocytosis, elicited by moderate and strong stimuli, respectively. They are tightly coupled with exocytosis for sustained neurotransmission. However, the underlying...

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Veröffentlicht in:	PLoS biology 2017-04, Vol.15 (4), p.e2000931-e2000931
Hauptverfasser:	Yao, Chi-Kuang, Liu, Yu-Tzu, Lee, I-Chi, Wang, You-Tung, Wu, Ping-Yen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Biology and Life Sciences Calcium - metabolism Calcium - pharmacology Calcium channels Calcium Channels - genetics Calcium Channels - metabolism Calcium ions Cell Line Channeling Chemistry Clathrin - metabolism Data collection Drosophila Drosophila Proteins - genetics Drosophila Proteins - metabolism Endocytosis Endocytosis - drug effects Endocytosis - physiology Exocytosis - physiology Funding Gene Knockdown Techniques Hippocampus Insects Lanthanum - pharmacology Medicine and Health Sciences Mice Mutation Neurons Neurons - metabolism Physical Sciences Physiology Protein Isoforms Proteins Rats Roles Software Stimulation Synapses Synapses - metabolism Synaptic vesicles Synaptic Vesicles - metabolism
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