Genome-wide association study of facial morphology reveals novel associations with FREM1 and PARK2

Several studies have now shown evidence of association between common genetic variants and quantitative facial traits in humans. The reported associations generally involve simple univariate measures and likely represent only a small fraction of the genetic loci influencing facial morphology. In thi...

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Veröffentlicht in:	PloS one 2017-04, Vol.12 (4), p.e0176566-e0176566
Hauptverfasser:	Lee, Myoung Keun, Shaffer, John R, Leslie, Elizabeth J, Orlova, Ekaterina, Carlson, Jenna C, Feingold, Eleanor, Marazita, Mary L, Weinberg, Seth M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animal models Anthropometry Biology Biology and Life Sciences Child Child, Preschool Chromosomes European Continental Ancestry Group - genetics Face - anatomy & histology Factor analysis Female Gene expression Genealogy Genetic aspects Genetic variance Genetic Variation Genetics Genome-wide association studies Genome-Wide Association Study Genomes Genotype Human subjects Humans Lead Male Medicine and Health Sciences Morphology Multivariate analysis Mutation Nucleotides Phenotype Phenotyping Physical Sciences Polymorphism Polymorphism, Single Nucleotide Public health Receptors, Interleukin - genetics Research and Analysis Methods Single nucleotide polymorphisms Single-nucleotide polymorphism Studies Ubiquitin-Protein Ligases - genetics Young Adult
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