Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership
Cystic echinococcosis (CE) is a neglected parasitic zoonosis with considerable socioeconomic impact on affected pastoral communities. CE is endemic throughout the Mediterranean, including Morocco, where the Mid Atlas is the most prevalent area for both human and animal infection. The highest hospita...
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| creator | Chebli, Houda Laamrani El Idrissi, Abderrhamane Benazzouz, Mustapha Lmimouni, Badre Eddine Nhammi, Haddou Elabandouni, Mourad Youbi, Mohammed Afifi, Rajaa Tahiri, Sara Essayd El Feydi, Abdellah Settaf, Adbellatif Tinelli, Carmine De Silvestri, Annalisa Bouhout, Souad Abela-Ridder, Bernadette Magnino, Simone Brunetti, Enrico Filice, Carlo Tamarozzi, Francesca |
| description | Cystic echinococcosis (CE) is a neglected parasitic zoonosis with considerable socioeconomic impact on affected pastoral communities. CE is endemic throughout the Mediterranean, including Morocco, where the Mid Atlas is the most prevalent area for both human and animal infection. The highest hospital annual incidence of human CE is recorded in the provinces of Ifrane and El Hajeb. However, hospital-based statistics likely underestimate the real prevalence of infection, as a proportion of cases never reach medical attention or official records.
In 2012, a project on clinical management of CE in Morocco was launched with the aims of estimating the prevalence of human abdominal CE in selected rural communes of the above mentioned provinces using ultrasound (US) screening and training local physicians to implement US-based focused assessment and rational clinical management of CE according to the WHO-IWGE Expert Consensus. A total of 5367 people received abdominal US during four campaigns in April-May 2014. During the campaigns, 24 local general practitioners received >24 hours of hands-on training and 143 health education sessions were organized for local communities. We found an overall CE prevalence of 1.9%, with significantly higher values in the rural communes of Ifrane than El Hajeb (2.6% vs 1.3%; p |
| doi_str_mv | 10.1371/journal.pntd.0005384 |
| format | Article |
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In 2012, a project on clinical management of CE in Morocco was launched with the aims of estimating the prevalence of human abdominal CE in selected rural communes of the above mentioned provinces using ultrasound (US) screening and training local physicians to implement US-based focused assessment and rational clinical management of CE according to the WHO-IWGE Expert Consensus. A total of 5367 people received abdominal US during four campaigns in April-May 2014. During the campaigns, 24 local general practitioners received >24 hours of hands-on training and 143 health education sessions were organized for local communities. We found an overall CE prevalence of 1.9%, with significantly higher values in the rural communes of Ifrane than El Hajeb (2.6% vs 1.3%; p<0.001). CE cysts were predominantly in inactive stage, especially in older age groups. However, active cysts were present also in adults, indicating acquisition of infection at all ages. Province of residence was the only risk factor consistently associated with CE infection.
Our results show a high prevalence and on-going, likely environmental transmission of CE in the investigated provinces of Morocco, supporting the implementation of control activities in the area by national health authorities and encouraging the acceptance and divulgation of diagnosis and treatment algorithms based on imaging for CE at both national and local level.</description><identifier>ISSN: 1935-2735</identifier><identifier>ISSN: 1935-2727</identifier><identifier>EISSN: 1935-2735</identifier><identifier>DOI: 10.1371/journal.pntd.0005384</identifier><identifier>PMID: 28248960</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abdomen ; Abdomen - diagnostic imaging ; Adolescent ; Adult ; Adults ; Age ; Aged ; Aged, 80 and over ; Agricultural management ; Agriculture ; Agronomy ; Albendazole ; Algorithms ; Alveoli ; Analysis ; Animal health ; Biology and Life Sciences ; Biometrics ; Child ; Child, Preschool ; Children ; Colleges & universities ; Cysts ; Diagnosis ; Division ; Echinococcosis ; Echinococcosis - diagnostic imaging ; Echinococcosis - epidemiology ; Epidemiology ; Female ; Food ; Fungi ; Health aspects ; Human behavior ; Human performance ; Humans ; Immune response ; Immune system ; Immunoglobulin G ; Incidence ; Infections ; Infectious diseases ; Integrated control ; International Cooperation ; Italy ; Livestock ; Male ; Manganese ; Mass Screening - methods ; Medical diagnosis ; Medicine ; Medicine and Health Sciences ; Middle Aged ; Morocco - epidemiology ; Parasites ; Parasitic diseases ; Parasitology ; Pediatrics ; People and Places ; Pharmacy ; Prevalence ; Project management ; Provinces ; Public health ; Risk factors ; Rural areas ; Rural Population ; Seroconversion ; Serology ; Statistical analysis ; Surgery ; Tropical diseases ; Ultrasonic imaging ; Ultrasonography - methods ; Ultrasound ; Young Adult ; Zoonoses</subject><ispartof>PLoS neglected tropical diseases, 2017-03, Vol.11 (3), p.e0005384-e0005384</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Chebli H, Laamrani El Idrissi A, Benazzouz M, Lmimouni BE, Nhammi H, Elabandouni M, et al. (2017) Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership. PLoS Negl Trop Dis 11(3): e0005384. https://doi.org/10.1371/journal.pntd.0005384</rights><rights>2017 Chebli et al 2017 Chebli et al</rights><rights>2017 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Chebli H, Laamrani El Idrissi A, Benazzouz M, Lmimouni BE, Nhammi H, Elabandouni M, et al. (2017) Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership. PLoS Negl Trop Dis 11(3): e0005384. https://doi.org/10.1371/journal.pntd.0005384</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c624t-16fda683e92ed90d1be677932b58959bfec75c4f9df2102d585b8fc4fdf2917b3</citedby><cites>FETCH-LOGICAL-c624t-16fda683e92ed90d1be677932b58959bfec75c4f9df2102d585b8fc4fdf2917b3</cites><orcidid>0000-0003-0478-3914</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348040/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348040/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,27901,27902,53766,53768,79342,79343</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28248960$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chebli, Houda</creatorcontrib><creatorcontrib>Laamrani El Idrissi, Abderrhamane</creatorcontrib><creatorcontrib>Benazzouz, Mustapha</creatorcontrib><creatorcontrib>Lmimouni, Badre Eddine</creatorcontrib><creatorcontrib>Nhammi, Haddou</creatorcontrib><creatorcontrib>Elabandouni, Mourad</creatorcontrib><creatorcontrib>Youbi, Mohammed</creatorcontrib><creatorcontrib>Afifi, Rajaa</creatorcontrib><creatorcontrib>Tahiri, Sara</creatorcontrib><creatorcontrib>Essayd El Feydi, Abdellah</creatorcontrib><creatorcontrib>Settaf, Adbellatif</creatorcontrib><creatorcontrib>Tinelli, Carmine</creatorcontrib><creatorcontrib>De Silvestri, Annalisa</creatorcontrib><creatorcontrib>Bouhout, Souad</creatorcontrib><creatorcontrib>Abela-Ridder, Bernadette</creatorcontrib><creatorcontrib>Magnino, Simone</creatorcontrib><creatorcontrib>Brunetti, Enrico</creatorcontrib><creatorcontrib>Filice, Carlo</creatorcontrib><creatorcontrib>Tamarozzi, Francesca</creatorcontrib><title>Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership</title><title>PLoS neglected tropical diseases</title><addtitle>PLoS Negl Trop Dis</addtitle><description>Cystic echinococcosis (CE) is a neglected parasitic zoonosis with considerable socioeconomic impact on affected pastoral communities. CE is endemic throughout the Mediterranean, including Morocco, where the Mid Atlas is the most prevalent area for both human and animal infection. The highest hospital annual incidence of human CE is recorded in the provinces of Ifrane and El Hajeb. However, hospital-based statistics likely underestimate the real prevalence of infection, as a proportion of cases never reach medical attention or official records.
In 2012, a project on clinical management of CE in Morocco was launched with the aims of estimating the prevalence of human abdominal CE in selected rural communes of the above mentioned provinces using ultrasound (US) screening and training local physicians to implement US-based focused assessment and rational clinical management of CE according to the WHO-IWGE Expert Consensus. A total of 5367 people received abdominal US during four campaigns in April-May 2014. During the campaigns, 24 local general practitioners received >24 hours of hands-on training and 143 health education sessions were organized for local communities. We found an overall CE prevalence of 1.9%, with significantly higher values in the rural communes of Ifrane than El Hajeb (2.6% vs 1.3%; p<0.001). CE cysts were predominantly in inactive stage, especially in older age groups. However, active cysts were present also in adults, indicating acquisition of infection at all ages. Province of residence was the only risk factor consistently associated with CE infection.
Our results show a high prevalence and on-going, likely environmental transmission of CE in the investigated provinces of Morocco, supporting the implementation of control activities in the area by national health authorities and encouraging the acceptance and divulgation of diagnosis and treatment algorithms based on imaging for CE at both national and local level.</description><subject>Abdomen</subject><subject>Abdomen - diagnostic imaging</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Adults</subject><subject>Age</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Agricultural management</subject><subject>Agriculture</subject><subject>Agronomy</subject><subject>Albendazole</subject><subject>Algorithms</subject><subject>Alveoli</subject><subject>Analysis</subject><subject>Animal health</subject><subject>Biology and Life Sciences</subject><subject>Biometrics</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Colleges & universities</subject><subject>Cysts</subject><subject>Diagnosis</subject><subject>Division</subject><subject>Echinococcosis</subject><subject>Echinococcosis - diagnostic imaging</subject><subject>Echinococcosis - epidemiology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Food</subject><subject>Fungi</subject><subject>Health aspects</subject><subject>Human behavior</subject><subject>Human performance</subject><subject>Humans</subject><subject>Immune response</subject><subject>Immune system</subject><subject>Immunoglobulin G</subject><subject>Incidence</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Integrated control</subject><subject>International Cooperation</subject><subject>Italy</subject><subject>Livestock</subject><subject>Male</subject><subject>Manganese</subject><subject>Mass Screening - methods</subject><subject>Medical diagnosis</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Middle Aged</subject><subject>Morocco - epidemiology</subject><subject>Parasites</subject><subject>Parasitic diseases</subject><subject>Parasitology</subject><subject>Pediatrics</subject><subject>People and Places</subject><subject>Pharmacy</subject><subject>Prevalence</subject><subject>Project management</subject><subject>Provinces</subject><subject>Public health</subject><subject>Risk factors</subject><subject>Rural areas</subject><subject>Rural Population</subject><subject>Seroconversion</subject><subject>Serology</subject><subject>Statistical analysis</subject><subject>Surgery</subject><subject>Tropical diseases</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonography - methods</subject><subject>Ultrasound</subject><subject>Young Adult</subject><subject>Zoonoses</subject><issn>1935-2735</issn><issn>1935-2727</issn><issn>1935-2735</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNptkl2P1CAUhhujcT_0HxhtYmK8mZGPUsALk8lG3Ul24417TSiFKRMGRqAm---lO93NjNn0gp7Dc15eDqeq3kGwhJjCL9swRi_dcu9zvwQAEMyaF9U55JgsEMXk5dH_WXWR0rYwnDD4ujpDDDWMt-C8Gq_HnfS1uk_ZqlqrwfqgglIh2VRbX9-GOEVf6zuXo0xh9H2dVNTaW7-ZgDzo-tb29So7mUoUw7gZ6iK5ztJZ6RcHhZLYy5i9jmmw-zfVKyNd0m_n9bK6-_H999X14ubXz_XV6mahWtTkBWxNL1uGNUe656CHnW4p5Rh1hHHCO6MVJaoxvDcIAtQTRjpmSqLEHNIOX1YfDrp7F5KYO5YEZIy1pMUUFWJ9IPogt2If7U7GexGkFQ-JEDei2LbKaQGobjvTSSQhbTRAkgDYYYIpBcBQxorWt_m0sdvpXmlfWuZORE93vB3EJvwVBDcMNKAIfJ4FYvgz6pTFzialnZNeh3HyTYvn8oywoB__Q5-_3UxtZLmA9SaUc9UkKlYNxwxSxCffy2eo8vV6Z1Xw2tiSPyn4dFQwaOnykIIbsw0-nYLNAVQxpBS1eWoGBGKa4kfXYppiMU9xKXt_3Minosexxf8A1lrvqw</recordid><startdate>201703</startdate><enddate>201703</enddate><creator>Chebli, Houda</creator><creator>Laamrani El Idrissi, Abderrhamane</creator><creator>Benazzouz, Mustapha</creator><creator>Lmimouni, Badre Eddine</creator><creator>Nhammi, Haddou</creator><creator>Elabandouni, Mourad</creator><creator>Youbi, Mohammed</creator><creator>Afifi, Rajaa</creator><creator>Tahiri, Sara</creator><creator>Essayd El Feydi, Abdellah</creator><creator>Settaf, Adbellatif</creator><creator>Tinelli, Carmine</creator><creator>De Silvestri, Annalisa</creator><creator>Bouhout, Souad</creator><creator>Abela-Ridder, Bernadette</creator><creator>Magnino, Simone</creator><creator>Brunetti, Enrico</creator><creator>Filice, Carlo</creator><creator>Tamarozzi, Francesca</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7SS</scope><scope>7T2</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>H95</scope><scope>H97</scope><scope>K9.</scope><scope>L.G</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>P64</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-0478-3914</orcidid></search><sort><creationdate>201703</creationdate><title>Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership</title><author>Chebli, Houda ; Laamrani El Idrissi, Abderrhamane ; Benazzouz, Mustapha ; Lmimouni, Badre Eddine ; Nhammi, Haddou ; Elabandouni, Mourad ; Youbi, Mohammed ; Afifi, Rajaa ; Tahiri, Sara ; Essayd El Feydi, Abdellah ; Settaf, Adbellatif ; Tinelli, Carmine ; De Silvestri, Annalisa ; Bouhout, Souad ; Abela-Ridder, Bernadette ; Magnino, Simone ; Brunetti, Enrico ; Filice, Carlo ; Tamarozzi, Francesca</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c624t-16fda683e92ed90d1be677932b58959bfec75c4f9df2102d585b8fc4fdf2917b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Abdomen</topic><topic>Abdomen - diagnostic imaging</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Adults</topic><topic>Age</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Agricultural management</topic><topic>Agriculture</topic><topic>Agronomy</topic><topic>Albendazole</topic><topic>Algorithms</topic><topic>Alveoli</topic><topic>Analysis</topic><topic>Animal health</topic><topic>Biology and Life Sciences</topic><topic>Biometrics</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Colleges & universities</topic><topic>Cysts</topic><topic>Diagnosis</topic><topic>Division</topic><topic>Echinococcosis</topic><topic>Echinococcosis - diagnostic imaging</topic><topic>Echinococcosis - epidemiology</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Food</topic><topic>Fungi</topic><topic>Health aspects</topic><topic>Human behavior</topic><topic>Human performance</topic><topic>Humans</topic><topic>Immune response</topic><topic>Immune system</topic><topic>Immunoglobulin G</topic><topic>Incidence</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Integrated control</topic><topic>International Cooperation</topic><topic>Italy</topic><topic>Livestock</topic><topic>Male</topic><topic>Manganese</topic><topic>Mass Screening - methods</topic><topic>Medical diagnosis</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Middle Aged</topic><topic>Morocco - epidemiology</topic><topic>Parasites</topic><topic>Parasitic diseases</topic><topic>Parasitology</topic><topic>Pediatrics</topic><topic>People and Places</topic><topic>Pharmacy</topic><topic>Prevalence</topic><topic>Project management</topic><topic>Provinces</topic><topic>Public health</topic><topic>Risk factors</topic><topic>Rural areas</topic><topic>Rural Population</topic><topic>Seroconversion</topic><topic>Serology</topic><topic>Statistical analysis</topic><topic>Surgery</topic><topic>Tropical diseases</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonography - methods</topic><topic>Ultrasound</topic><topic>Young Adult</topic><topic>Zoonoses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chebli, Houda</creatorcontrib><creatorcontrib>Laamrani El Idrissi, Abderrhamane</creatorcontrib><creatorcontrib>Benazzouz, Mustapha</creatorcontrib><creatorcontrib>Lmimouni, Badre Eddine</creatorcontrib><creatorcontrib>Nhammi, Haddou</creatorcontrib><creatorcontrib>Elabandouni, Mourad</creatorcontrib><creatorcontrib>Youbi, Mohammed</creatorcontrib><creatorcontrib>Afifi, Rajaa</creatorcontrib><creatorcontrib>Tahiri, Sara</creatorcontrib><creatorcontrib>Essayd El Feydi, Abdellah</creatorcontrib><creatorcontrib>Settaf, Adbellatif</creatorcontrib><creatorcontrib>Tinelli, Carmine</creatorcontrib><creatorcontrib>De Silvestri, Annalisa</creatorcontrib><creatorcontrib>Bouhout, Souad</creatorcontrib><creatorcontrib>Abela-Ridder, Bernadette</creatorcontrib><creatorcontrib>Magnino, Simone</creatorcontrib><creatorcontrib>Brunetti, Enrico</creatorcontrib><creatorcontrib>Filice, Carlo</creatorcontrib><creatorcontrib>Tamarozzi, Francesca</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PLoS neglected tropical diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chebli, Houda</au><au>Laamrani El Idrissi, Abderrhamane</au><au>Benazzouz, Mustapha</au><au>Lmimouni, Badre Eddine</au><au>Nhammi, Haddou</au><au>Elabandouni, Mourad</au><au>Youbi, Mohammed</au><au>Afifi, Rajaa</au><au>Tahiri, Sara</au><au>Essayd El Feydi, Abdellah</au><au>Settaf, Adbellatif</au><au>Tinelli, Carmine</au><au>De Silvestri, Annalisa</au><au>Bouhout, Souad</au><au>Abela-Ridder, Bernadette</au><au>Magnino, Simone</au><au>Brunetti, Enrico</au><au>Filice, Carlo</au><au>Tamarozzi, Francesca</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership</atitle><jtitle>PLoS neglected tropical diseases</jtitle><addtitle>PLoS Negl Trop Dis</addtitle><date>2017-03</date><risdate>2017</risdate><volume>11</volume><issue>3</issue><spage>e0005384</spage><epage>e0005384</epage><pages>e0005384-e0005384</pages><issn>1935-2735</issn><issn>1935-2727</issn><eissn>1935-2735</eissn><abstract>Cystic echinococcosis (CE) is a neglected parasitic zoonosis with considerable socioeconomic impact on affected pastoral communities. CE is endemic throughout the Mediterranean, including Morocco, where the Mid Atlas is the most prevalent area for both human and animal infection. The highest hospital annual incidence of human CE is recorded in the provinces of Ifrane and El Hajeb. However, hospital-based statistics likely underestimate the real prevalence of infection, as a proportion of cases never reach medical attention or official records.
In 2012, a project on clinical management of CE in Morocco was launched with the aims of estimating the prevalence of human abdominal CE in selected rural communes of the above mentioned provinces using ultrasound (US) screening and training local physicians to implement US-based focused assessment and rational clinical management of CE according to the WHO-IWGE Expert Consensus. A total of 5367 people received abdominal US during four campaigns in April-May 2014. During the campaigns, 24 local general practitioners received >24 hours of hands-on training and 143 health education sessions were organized for local communities. We found an overall CE prevalence of 1.9%, with significantly higher values in the rural communes of Ifrane than El Hajeb (2.6% vs 1.3%; p<0.001). CE cysts were predominantly in inactive stage, especially in older age groups. However, active cysts were present also in adults, indicating acquisition of infection at all ages. Province of residence was the only risk factor consistently associated with CE infection.
Our results show a high prevalence and on-going, likely environmental transmission of CE in the investigated provinces of Morocco, supporting the implementation of control activities in the area by national health authorities and encouraging the acceptance and divulgation of diagnosis and treatment algorithms based on imaging for CE at both national and local level.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28248960</pmid><doi>10.1371/journal.pntd.0005384</doi><orcidid>https://orcid.org/0000-0003-0478-3914</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1935-2735 |
| ispartof | PLoS neglected tropical diseases, 2017-03, Vol.11 (3), p.e0005384-e0005384 |
| issn | 1935-2735 1935-2727 1935-2735 |
| language | eng |
| recordid | cdi_plos_journals_1888656372 |
| source | Public Library of Science (PLoS) Journals Open Access; MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; PubMed Central Open Access |
| subjects | Abdomen Abdomen - diagnostic imaging Adolescent Adult Adults Age Aged Aged, 80 and over Agricultural management Agriculture Agronomy Albendazole Algorithms Alveoli Analysis Animal health Biology and Life Sciences Biometrics Child Child, Preschool Children Colleges & universities Cysts Diagnosis Division Echinococcosis Echinococcosis - diagnostic imaging Echinococcosis - epidemiology Epidemiology Female Food Fungi Health aspects Human behavior Human performance Humans Immune response Immune system Immunoglobulin G Incidence Infections Infectious diseases Integrated control International Cooperation Italy Livestock Male Manganese Mass Screening - methods Medical diagnosis Medicine Medicine and Health Sciences Middle Aged Morocco - epidemiology Parasites Parasitic diseases Parasitology Pediatrics People and Places Pharmacy Prevalence Project management Provinces Public health Risk factors Rural areas Rural Population Seroconversion Serology Statistical analysis Surgery Tropical diseases Ultrasonic imaging Ultrasonography - methods Ultrasound Young Adult Zoonoses |
| title | Human cystic echinococcosis in Morocco: Ultrasound screening in the Mid Atlas through an Italian-Moroccan partnership |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-07T11%3A06%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Human%20cystic%20echinococcosis%20in%20Morocco:%20Ultrasound%20screening%20in%20the%20Mid%20Atlas%20through%20an%20Italian-Moroccan%20partnership&rft.jtitle=PLoS%20neglected%20tropical%20diseases&rft.au=Chebli,%20Houda&rft.date=2017-03&rft.volume=11&rft.issue=3&rft.spage=e0005384&rft.epage=e0005384&rft.pages=e0005384-e0005384&rft.issn=1935-2735&rft.eissn=1935-2735&rft_id=info:doi/10.1371/journal.pntd.0005384&rft_dat=%3Cgale_plos_%3EA493817298%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1888656372&rft_id=info:pmid/28248960&rft_galeid=A493817298&rft_doaj_id=oai_doaj_org_article_07e6bfba2a174e02a501b3537700f788&rfr_iscdi=true |