Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets
To calculate an optimal collimator angle at each of sectional arcs in a full-arc volumetric modulated arc therapy (VMAT) plan and evaluate dosimetric quality of these VMAT plans comparing full-arc VMAT plans with a fixed collimator angle. Seventeen patients who had irregularly-shaped target in abdom...
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| creator | Ahn, Beom Seok Park, So-Yeon Park, Jong Min Choi, Chang Heon Chun, Minsoo Kim, Jung-In |
| description | To calculate an optimal collimator angle at each of sectional arcs in a full-arc volumetric modulated arc therapy (VMAT) plan and evaluate dosimetric quality of these VMAT plans comparing full-arc VMAT plans with a fixed collimator angle.
Seventeen patients who had irregularly-shaped target in abdominal, head and neck, and chest cases were selected retrospectively. To calculate an optimal collimator angle at each of sectional arcs in VMAT, integrated MLC apertures which could cover all shapes of target determined by beam's-eye view (BEV) within angular sections were obtained for each VMAT plan. The angular sections were 40°, 60°, 90° and 120°. When the collimator settings were rotated at intervals of 2°, we obtained the optimal collimator angle to minimize area size difference between the integrated MLC aperture and collimator settings with 5 mm-margins to the integrated MLC aperture. The VMAT plans with the optimal collimator angles (Colli-VMAT) were generated in the EclipseTM. For comparison purposes, one full-arc VMAT plans with a fixed collimator angles (Std-VMAT) were generated. The dose-volumetric parameters and total MUs were evaluated.
The mean dose-volumetric parameters for target volume of Colli-VMAT were comparable to Std-VMAT. Colli-VMAT improved sparing of most normal organs but for brain stem, compared to Std-VMAT for all cases. There were decreasing tendencies in mean total MUs with decreasing angular section. The mean total MUs for Colli-VMAT with the angular section of 40° (434 ± 95 MU, 317 ± 81 MU, and 371 ± 43 MU for abdominal, head and neck, and chest cases, respectively) were lower than those for Std-VMAT (654 ± 182 MU, 517 ± 116 MU, and 533 ± 25 MU, respectively).
For an irregularly-shaped target, Colli-VMAT with the angular section of 40° reduced total MUs and improved sparing of normal organs, compared to Std-VMAT. |
| doi_str_mv | 10.1371/journal.pone.0174924 |
| format | Article |
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Seventeen patients who had irregularly-shaped target in abdominal, head and neck, and chest cases were selected retrospectively. To calculate an optimal collimator angle at each of sectional arcs in VMAT, integrated MLC apertures which could cover all shapes of target determined by beam's-eye view (BEV) within angular sections were obtained for each VMAT plan. The angular sections were 40°, 60°, 90° and 120°. When the collimator settings were rotated at intervals of 2°, we obtained the optimal collimator angle to minimize area size difference between the integrated MLC aperture and collimator settings with 5 mm-margins to the integrated MLC aperture. The VMAT plans with the optimal collimator angles (Colli-VMAT) were generated in the EclipseTM. For comparison purposes, one full-arc VMAT plans with a fixed collimator angles (Std-VMAT) were generated. The dose-volumetric parameters and total MUs were evaluated.
The mean dose-volumetric parameters for target volume of Colli-VMAT were comparable to Std-VMAT. Colli-VMAT improved sparing of most normal organs but for brain stem, compared to Std-VMAT for all cases. There were decreasing tendencies in mean total MUs with decreasing angular section. The mean total MUs for Colli-VMAT with the angular section of 40° (434 ± 95 MU, 317 ± 81 MU, and 371 ± 43 MU for abdominal, head and neck, and chest cases, respectively) were lower than those for Std-VMAT (654 ± 182 MU, 517 ± 116 MU, and 533 ± 25 MU, respectively).
For an irregularly-shaped target, Colli-VMAT with the angular section of 40° reduced total MUs and improved sparing of normal organs, compared to Std-VMAT.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0174924</identifier><identifier>PMID: 28384262</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abdomen ; Apertures ; Biology and Life Sciences ; Biomedical research ; Brain ; Brain stem ; Cancer therapies ; Chest ; Collimation ; Collimators (Optical instruments) ; Dosimeters ; Dosimetry ; Drug dosages ; Head and neck ; Humans ; Liver cancer ; Mathematical analysis ; Medical research ; Medicine ; Medicine and Health Sciences ; Monte Carlo simulation ; Oncology ; Organs ; Patients ; Physical Sciences ; Physicians ; Planning ; Principal components analysis ; Prostate cancer ; Radiation therapy ; Radiotherapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted - instrumentation ; Radiotherapy Planning, Computer-Assisted - methods ; Spinal cord ; Studies ; Therapy</subject><ispartof>PloS one, 2017-04, Vol.12 (4), p.e0174924-e0174924</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Ahn et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Ahn et al 2017 Ahn et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-390b09faab4bbbb26d03eb575053ab2b8cf2247b6b051ebc625cf517f01307e23</citedby><cites>FETCH-LOGICAL-c692t-390b09faab4bbbb26d03eb575053ab2b8cf2247b6b051ebc625cf517f01307e23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383152/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383152/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28384262$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Zhang, Qinghui</contributor><creatorcontrib>Ahn, Beom Seok</creatorcontrib><creatorcontrib>Park, So-Yeon</creatorcontrib><creatorcontrib>Park, Jong Min</creatorcontrib><creatorcontrib>Choi, Chang Heon</creatorcontrib><creatorcontrib>Chun, Minsoo</creatorcontrib><creatorcontrib>Kim, Jung-In</creatorcontrib><title>Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To calculate an optimal collimator angle at each of sectional arcs in a full-arc volumetric modulated arc therapy (VMAT) plan and evaluate dosimetric quality of these VMAT plans comparing full-arc VMAT plans with a fixed collimator angle.
Seventeen patients who had irregularly-shaped target in abdominal, head and neck, and chest cases were selected retrospectively. To calculate an optimal collimator angle at each of sectional arcs in VMAT, integrated MLC apertures which could cover all shapes of target determined by beam's-eye view (BEV) within angular sections were obtained for each VMAT plan. The angular sections were 40°, 60°, 90° and 120°. When the collimator settings were rotated at intervals of 2°, we obtained the optimal collimator angle to minimize area size difference between the integrated MLC aperture and collimator settings with 5 mm-margins to the integrated MLC aperture. The VMAT plans with the optimal collimator angles (Colli-VMAT) were generated in the EclipseTM. For comparison purposes, one full-arc VMAT plans with a fixed collimator angles (Std-VMAT) were generated. The dose-volumetric parameters and total MUs were evaluated.
The mean dose-volumetric parameters for target volume of Colli-VMAT were comparable to Std-VMAT. Colli-VMAT improved sparing of most normal organs but for brain stem, compared to Std-VMAT for all cases. There were decreasing tendencies in mean total MUs with decreasing angular section. The mean total MUs for Colli-VMAT with the angular section of 40° (434 ± 95 MU, 317 ± 81 MU, and 371 ± 43 MU for abdominal, head and neck, and chest cases, respectively) were lower than those for Std-VMAT (654 ± 182 MU, 517 ± 116 MU, and 533 ± 25 MU, respectively).
For an irregularly-shaped target, Colli-VMAT with the angular section of 40° reduced total MUs and improved sparing of normal organs, compared to Std-VMAT.</description><subject>Abdomen</subject><subject>Apertures</subject><subject>Biology and Life Sciences</subject><subject>Biomedical research</subject><subject>Brain</subject><subject>Brain stem</subject><subject>Cancer therapies</subject><subject>Chest</subject><subject>Collimation</subject><subject>Collimators (Optical instruments)</subject><subject>Dosimeters</subject><subject>Dosimetry</subject><subject>Drug dosages</subject><subject>Head and neck</subject><subject>Humans</subject><subject>Liver cancer</subject><subject>Mathematical analysis</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Monte Carlo simulation</subject><subject>Oncology</subject><subject>Organs</subject><subject>Patients</subject><subject>Physical Sciences</subject><subject>Physicians</subject><subject>Planning</subject><subject>Principal components analysis</subject><subject>Prostate cancer</subject><subject>Radiation therapy</subject><subject>Radiotherapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy Planning, Computer-Assisted - instrumentation</subject><subject>Radiotherapy Planning, Computer-Assisted - methods</subject><subject>Spinal cord</subject><subject>Studies</subject><subject>Therapy</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1uL1DAUx4so7rr6DUQLgujDjLm0SfsiLOttYGHB22tI06STIW1mk3Rxnv3innG6y1T2weahIfmd_8m5ZdlzjJaYcvxu48cwSLfc-kEvEeZFTYoH2SmuKVkwgujDo_1J9iTGDUIlrRh7nJ2QilYFYeQ0-_3BR9vrFKzKtTFapZh7k0fYWA_yuWw3Y0y9Hg4Xyjtne5l8yOXQOQ2HQ37j3Thp9L4dnUy6zWVQeVrrILe73ABuQ9Ad3AW3W8S13AKSZOh0ik-zR0a6qJ9N_7Psx6eP3y--LC6vPq8uzi8XitUkLWiNGlQbKZuigY-wFlHdlLyEsGRDmkoZQgresAaVWDeKkVKZEnODMEVcE3qWvTzobp2PYspfFLiqSsQ5xRiI1YFovdyIbYBIw054acXfAx86IUOyymnBOHhTTYUNpwXVZYU5k7hqaM0klIKD1vvJ29j0ulWQwSDdTHR-M9i16PyNgCJRXO6f-2YSCP561DGJ3kalnZOD9uPh3XVJSMkAffUPen90E9VJCMAOxoNftRcV50VNOSsqXAC1vIeC1ereKmg2Y-F8ZvB2ZgBM0r9SJ8cYxerb1_9nr37O2ddH7FpLl9YROm3fmHEOFgdQBR9j0OYuyRiJ_azcZkPsZ0VMswJmL44LdGd0Oxz0D6UDETA</recordid><startdate>20170406</startdate><enddate>20170406</enddate><creator>Ahn, Beom Seok</creator><creator>Park, So-Yeon</creator><creator>Park, Jong Min</creator><creator>Choi, Chang Heon</creator><creator>Chun, Minsoo</creator><creator>Kim, Jung-In</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20170406</creationdate><title>Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets</title><author>Ahn, Beom Seok ; Park, So-Yeon ; Park, Jong Min ; Choi, Chang Heon ; Chun, Minsoo ; Kim, Jung-In</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-390b09faab4bbbb26d03eb575053ab2b8cf2247b6b051ebc625cf517f01307e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Abdomen</topic><topic>Apertures</topic><topic>Biology and Life Sciences</topic><topic>Biomedical research</topic><topic>Brain</topic><topic>Brain stem</topic><topic>Cancer therapies</topic><topic>Chest</topic><topic>Collimation</topic><topic>Collimators (Optical instruments)</topic><topic>Dosimeters</topic><topic>Dosimetry</topic><topic>Drug dosages</topic><topic>Head and neck</topic><topic>Humans</topic><topic>Liver cancer</topic><topic>Mathematical analysis</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Monte Carlo simulation</topic><topic>Oncology</topic><topic>Organs</topic><topic>Patients</topic><topic>Physical Sciences</topic><topic>Physicians</topic><topic>Planning</topic><topic>Principal components analysis</topic><topic>Prostate cancer</topic><topic>Radiation therapy</topic><topic>Radiotherapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy Planning, Computer-Assisted - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ahn, Beom Seok</au><au>Park, So-Yeon</au><au>Park, Jong Min</au><au>Choi, Chang Heon</au><au>Chun, Minsoo</au><au>Kim, Jung-In</au><au>Zhang, Qinghui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-04-06</date><risdate>2017</risdate><volume>12</volume><issue>4</issue><spage>e0174924</spage><epage>e0174924</epage><pages>e0174924-e0174924</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To calculate an optimal collimator angle at each of sectional arcs in a full-arc volumetric modulated arc therapy (VMAT) plan and evaluate dosimetric quality of these VMAT plans comparing full-arc VMAT plans with a fixed collimator angle.
Seventeen patients who had irregularly-shaped target in abdominal, head and neck, and chest cases were selected retrospectively. To calculate an optimal collimator angle at each of sectional arcs in VMAT, integrated MLC apertures which could cover all shapes of target determined by beam's-eye view (BEV) within angular sections were obtained for each VMAT plan. The angular sections were 40°, 60°, 90° and 120°. When the collimator settings were rotated at intervals of 2°, we obtained the optimal collimator angle to minimize area size difference between the integrated MLC aperture and collimator settings with 5 mm-margins to the integrated MLC aperture. The VMAT plans with the optimal collimator angles (Colli-VMAT) were generated in the EclipseTM. For comparison purposes, one full-arc VMAT plans with a fixed collimator angles (Std-VMAT) were generated. The dose-volumetric parameters and total MUs were evaluated.
The mean dose-volumetric parameters for target volume of Colli-VMAT were comparable to Std-VMAT. Colli-VMAT improved sparing of most normal organs but for brain stem, compared to Std-VMAT for all cases. There were decreasing tendencies in mean total MUs with decreasing angular section. The mean total MUs for Colli-VMAT with the angular section of 40° (434 ± 95 MU, 317 ± 81 MU, and 371 ± 43 MU for abdominal, head and neck, and chest cases, respectively) were lower than those for Std-VMAT (654 ± 182 MU, 517 ± 116 MU, and 533 ± 25 MU, respectively).
For an irregularly-shaped target, Colli-VMAT with the angular section of 40° reduced total MUs and improved sparing of normal organs, compared to Std-VMAT.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28384262</pmid><doi>10.1371/journal.pone.0174924</doi><tpages>e0174924</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS); EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Abdomen Apertures Biology and Life Sciences Biomedical research Brain Brain stem Cancer therapies Chest Collimation Collimators (Optical instruments) Dosimeters Dosimetry Drug dosages Head and neck Humans Liver cancer Mathematical analysis Medical research Medicine Medicine and Health Sciences Monte Carlo simulation Oncology Organs Patients Physical Sciences Physicians Planning Principal components analysis Prostate cancer Radiation therapy Radiotherapy Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted - instrumentation Radiotherapy Planning, Computer-Assisted - methods Spinal cord Studies Therapy |
| title | Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T03%3A48%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dosimetric%20effects%20of%20sectional%20adjustments%20of%20collimator%20angles%20on%20volumetric%20modulated%20arc%20therapy%20for%20irregularly-shaped%20targets&rft.jtitle=PloS%20one&rft.au=Ahn,%20Beom%20Seok&rft.date=2017-04-06&rft.volume=12&rft.issue=4&rft.spage=e0174924&rft.epage=e0174924&rft.pages=e0174924-e0174924&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0174924&rft_dat=%3Cgale_plos_%3EA493764814%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1885077311&rft_id=info:pmid/28384262&rft_galeid=A493764814&rft_doaj_id=oai_doaj_org_article_67f22cb81f7343e58176a18b396a4927&rfr_iscdi=true |