Electrochemical sensor for rapid determination of fibroblast growth factor receptor 4 in raw cancer cell lysates

The first electrochemical immunosensor for the determination of fibroblast growth factor receptor 4 (FGFR4) biomarker is reported in this work. The biosensor involves a sandwich configuration with covalent immobilization of a specific capture antibody onto activated carboxylic-modified magnetic micr...

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Veröffentlicht in:	PloS one 2017-04, Vol.12 (4), p.e0175056-e0175056
Hauptverfasser:	Torrente-Rodríguez, Rebeca M, Ruiz-Valdepeñas Montiel, Víctor, Campuzano, Susana, Pedrero, María, Farchado, Meryem, Vargas, Eva, Manuel de Villena, F Javier, Garranzo-Asensio, María, Barderas, Rodrigo, Pingarrón, José M
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated carbon Biology and Life Sciences Biomarkers Biomarkers, Tumor - analysis Biosensing Techniques - methods Biosensing Techniques - statistics & numerical data Biosensors Breast cancer Cancer Cancer cells Carbon Cell Line, Tumor Chemical detectors Chemical sensors Colorectal cancer Dilution Electrical measurement Electrochemical Techniques Electrochemistry Electrodes Enzyme-Linked Immunosorbent Assay Fibroblast Growth Factor 4 - analysis Fibroblast growth factor receptors Fibroblasts Gene amplification Growth factor receptors Growth factors Humans Immobilization Immunoassay - methods Immunosensors Instrumentation Limit of Detection Magnetics MCF-7 Cells Medical diagnosis Medical prognosis Medicine and Health Sciences Physical Sciences Proteins Proteomics Receptors Research and Analysis Methods Selectivity Target detection
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