Quantification of intrapancreatic fat in type 2 diabetes by MRI

Accumulation of intrapancreatic fat may be important in type 2 diabetes, but widely varying data have been reported. The standard quantification by MRI in vivo is time consuming and dependent upon a high level of experience. We aimed to develop a new method which would minimise inter-observer variat...

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Veröffentlicht in:	PloS one 2017-04, Vol.12 (4), p.e0174660
Hauptverfasser:	Al-Mrabeh, Ahmad, Hollingsworth, Kieren G, Steven, Sarah, Tiniakos, Dina, Taylor, Roy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adolescent Adult Aged Autoimmune diseases Biology and Life Sciences Blood glucose Care and treatment Coefficient of variation Datasets Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 - physiopathology Female Gastroenterology Health aspects Humans Image analysis Image Processing, Computer-Assisted Immunology Insulin resistance Intra-Abdominal Fat - diagnostic imaging Intra-Abdominal Fat - physiology Lipids Liver diseases Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine and Health Sciences Metabolism Middle Aged NMR Nuclear magnetic resonance Obesity Observer Variation Oxidative stress Pancreas Pancreas - diagnostic imaging Pancreas - physiology Parenchymal Tissue - diagnostic imaging Parenchymal Tissue - physiology Reproducibility of Results Research and Analysis Methods Rodents Studies Tissues Type 2 diabetes Weight control Young Adult
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