RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides

Locomotor activity rhythms are controlled by a network of ~150 circadian neurons within the adult Drosophila brain. They are subdivided based on their anatomical locations and properties. We profiled transcripts "around the clock" from three key groups of circadian neurons with different f...

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Veröffentlicht in:	PLoS genetics 2017-02, Vol.13 (2), p.e1006613-e1006613
Hauptverfasser:	Abruzzi, Katharine C, Zadina, Abigail, Luo, Weifei, Wiyanto, Evelyn, Rahman, Reazur, Guo, Fang, Shafer, Orie, Rosbash, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Animals, Genetically Modified Behavior Biology Biology and Life Sciences Brain Brain - cytology Brain - metabolism Circadian Clocks - genetics Circadian rhythm Dopaminergic Neurons - metabolism Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins - genetics Feedback Funding Gene expression Gene Expression Profiling - methods Genetic aspects Genomics Insects Microscopy, Fluorescence Neurons Neurons - metabolism Neuropeptides Neuropeptides - genetics Neurosciences Oligonucleotide Array Sequence Analysis Research and Analysis Methods RNA sequencing Rodents Sequence Analysis, RNA - methods Sleep Time Factors Transcription factors Transcription Factors - genetics
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