Chronic social stress in pigs impairs intestinal barrier and nutrient transporter function, and alters neuro-immune mediator and receptor expression

Psychosocial stress is a major factor driving gastrointestinal (GI) pathophysiology and disease susceptibility in humans and animals. The mechanisms governing susceptibility to stress-induced GI disease remain poorly understood. In the present study, we investigated the influence of chronic social s...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0171617-e0171617
Hauptverfasser:	Li, Yihang, Song, Zehe, Kerr, Katelyn A, Moeser, Adam J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport Biology Biology and Life Sciences Biomarkers Body weight Body weight gain Cellular signal transduction Chymase Colon Colon - metabolism Corticotropin-releasing hormone Corticotropin-Releasing Hormone - genetics Corticotropin-Releasing Hormone - metabolism Cytokines Cytokines - genetics Cytokines - metabolism Dendritic cells Disease Feed efficiency Gene Expression Glucose Glucose - metabolism Glucose transporter Health aspects Hogs Hydrocortisone - blood Ileum Ileum - metabolism Immune response Immune system Immunology Inflammation Inflammatory bowel disease Interleukin 1 Interleukin 10 Interleukin 6 Interleukin 8 Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestine Irritable bowel syndrome Laboratory animals Medicine and Health Sciences Motility Neuroimmunomodulation - genetics Neuroimmunomodulation - immunology Nutrient interactions Nutrient transport Nutrients Observations Permeability Pigs Receptors, Cell Surface - genetics Rodents Short circuits Short-circuit current Signaling Social interactions Social Sciences Sodium Stress (Psychology) Stress, Psychological Stresses Swine Transport Tumor necrosis factor-α Urocortin Veterinary colleges Veterinary medicine Villus Weight reduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!