Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis

Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sed...

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Veröffentlicht in:PloS one 2017-03, Vol.12 (3), p.e0172253-e0172253
Hauptverfasser: Rosique-Esteban, Nuria, Díaz-López, Andrés, Martínez-González, Miguel A, Corella, Dolores, Goday, Albert, Martínez, J Alfredo, Romaguera, Dora, Vioque, Jesus, Arós, Fernando, Garcia-Rios, Antonio, Tinahones, Francisco, Estruch, Ramon, Fernández-García, José Carlos, Lapetra, José, Serra-Majem, Luís, Pinto, Xavier, Tur, Josep A, Bueno-Cavanillas, Aurora, Vidal, Josep, Delgado-Rodríguez, Miguel, Daimiel, Lidia, Vázquez, Clotilde, Rubio, Miguel Ángel, Ros, Emilio, Salas-Salvadó, Jordi
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container_volume 12
creator Rosique-Esteban, Nuria
Díaz-López, Andrés
Martínez-González, Miguel A
Corella, Dolores
Goday, Albert
Martínez, J Alfredo
Romaguera, Dora
Vioque, Jesus
Arós, Fernando
Garcia-Rios, Antonio
Tinahones, Francisco
Estruch, Ramon
Fernández-García, José Carlos
Lapetra, José
Serra-Majem, Luís
Pinto, Xavier
Tur, Josep A
Bueno-Cavanillas, Aurora
Vidal, Josep
Delgado-Rodríguez, Miguel
Daimiel, Lidia
Vázquez, Clotilde
Rubio, Miguel Ángel
Ros, Emilio
Salas-Salvadó, Jordi
description Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS trial. Employing multivariable-adjusted Cox regression with robust variance and constant time (given the cross-sectional design), higher prevalence of obesity, T2D and abdominal obesity as component of the MetS were associated with greater time in TV-viewing (Relative Risk, RR: 1.02, 95%CI: 1.01, 1.03; RR:1.04, 95%CI: 1.02, 1.06 and RR: 1.01 95%CI: 1.00, 1.02; respectively, all P < .01). Conversely, greater time in moderate-vigorous PA (MVPA) was associated with lower prevalence of obesity, T2D, abdominal obesity and low HDL-cholesterol (RR: 0.95, 95%CI: 0.93, 0.97; RR: 0.94, 95%CI: 0.89, 0.99; RR: 0.97, 95%CI: 0.96, 0.98; and RR: 0.95, 95%CI: 0.91, 0.99, respectively, all P < .05). For these outcomes, theoretically substituting 1-h/day of MVPA for 1-h/day TV-viewing was also significantly associated with lower prevalence (RR 0.91 to 0.97, all P < .05). Similar lower RR in these outcomes was observed when substituting 1-h/day of MVPA for 1-h/day of sleeping. Longer time watching TV and not meeting MVPA recommendations were jointly associated with higher RR of the prevalence of obesity and T2D. We concluded that, in senior individuals at high cardiovascular risk, greater time spent on MVPA and fewer on sedentary behaviors was inversely associated with prevalence of obesity, T2D, and some of the components of MetS.
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Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS trial. Employing multivariable-adjusted Cox regression with robust variance and constant time (given the cross-sectional design), higher prevalence of obesity, T2D and abdominal obesity as component of the MetS were associated with greater time in TV-viewing (Relative Risk, RR: 1.02, 95%CI: 1.01, 1.03; RR:1.04, 95%CI: 1.02, 1.06 and RR: 1.01 95%CI: 1.00, 1.02; respectively, all P &lt; .01). Conversely, greater time in moderate-vigorous PA (MVPA) was associated with lower prevalence of obesity, T2D, abdominal obesity and low HDL-cholesterol (RR: 0.95, 95%CI: 0.93, 0.97; RR: 0.94, 95%CI: 0.89, 0.99; RR: 0.97, 95%CI: 0.96, 0.98; and RR: 0.95, 95%CI: 0.91, 0.99, respectively, all P &lt; .05). For these outcomes, theoretically substituting 1-h/day of MVPA for 1-h/day TV-viewing was also significantly associated with lower prevalence (RR 0.91 to 0.97, all P &lt; .05). Similar lower RR in these outcomes was observed when substituting 1-h/day of MVPA for 1-h/day of sleeping. Longer time watching TV and not meeting MVPA recommendations were jointly associated with higher RR of the prevalence of obesity and T2D. We concluded that, in senior individuals at high cardiovascular risk, greater time spent on MVPA and fewer on sedentary behaviors was inversely associated with prevalence of obesity, T2D, and some of the components of MetS.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0172253</identifier><identifier>PMID: 28273154</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adults ; Aged ; Analysis ; Biochemistry ; Biology and Life Sciences ; Biomarkers ; Biomedical research ; Biotechnology ; Body weight ; Cardiovascular disease ; Cardiovascular diseases ; Cardiovascular Diseases - complications ; Cholesterol ; Clinical trials ; Cross-Sectional Studies ; Data processing ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - etiology ; Diabetis no-insulinodependent ; Disease prevention ; Endocrinology ; Epidemiologia ; Epidemiology ; Etiologia ; Etiology ; Exercise ; Factors de risc en les malalties ; Female ; Health behavior ; Health care ; Health risks ; Health sciences ; High density lipoprotein ; Hospitals ; Humans ; Hàbits sanitaris ; Internal medicine ; Internet ; Lipids ; Male ; Medical research ; Medicine and Health Sciences ; Metabolic disorders ; Metabolic syndrome ; Metabolic Syndrome - epidemiology ; Metabolic Syndrome - etiology ; Metabolism ; Middle Aged ; Non-insulin-dependent diabetes ; Nutrition research ; Obesity ; Odds Ratio ; Overweight ; Physical activity ; Physical fitness ; Prevalence ; Preventive medicine ; Public health ; Regression analysis ; Risk analysis ; Risk Factors ; Risk factors in diseases ; Risk taking ; Robustness (mathematics) ; Sedentary Behavior ; Sleep ; Son ; Spain - epidemiology ; Systematic review ; Síndrome metabòlica ; Type 2 diabetes ; Viewing</subject><ispartof>PloS one, 2017-03, Vol.12 (3), p.e0172253-e0172253</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Rosique-Esteban et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>cc-by (c) Rosique-Esteban, Nuria et al., 2017 info:eu-repo/semantics/openAccess &lt;a href="http://creativecommons.org/licenses/by/3.0/es"&gt;http://creativecommons.org/licenses/by/3.0/es&lt;/a&gt;</rights><rights>2017 Rosique-Esteban et al 2017 Rosique-Esteban et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c767t-5f77b20213cb20cdfcff535d5f02219f817c7aa204d6fde499cc4bae63ec47d43</citedby><cites>FETCH-LOGICAL-c767t-5f77b20213cb20cdfcff535d5f02219f817c7aa204d6fde499cc4bae63ec47d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342184/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342184/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,860,881,2096,2915,23845,26951,27901,27902,53766,53768,79343,79344</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28273154$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rosique-Esteban, Nuria</creatorcontrib><creatorcontrib>Díaz-López, Andrés</creatorcontrib><creatorcontrib>Martínez-González, Miguel A</creatorcontrib><creatorcontrib>Corella, Dolores</creatorcontrib><creatorcontrib>Goday, Albert</creatorcontrib><creatorcontrib>Martínez, J Alfredo</creatorcontrib><creatorcontrib>Romaguera, Dora</creatorcontrib><creatorcontrib>Vioque, Jesus</creatorcontrib><creatorcontrib>Arós, Fernando</creatorcontrib><creatorcontrib>Garcia-Rios, Antonio</creatorcontrib><creatorcontrib>Tinahones, Francisco</creatorcontrib><creatorcontrib>Estruch, Ramon</creatorcontrib><creatorcontrib>Fernández-García, José Carlos</creatorcontrib><creatorcontrib>Lapetra, José</creatorcontrib><creatorcontrib>Serra-Majem, Luís</creatorcontrib><creatorcontrib>Pinto, Xavier</creatorcontrib><creatorcontrib>Tur, Josep A</creatorcontrib><creatorcontrib>Bueno-Cavanillas, Aurora</creatorcontrib><creatorcontrib>Vidal, Josep</creatorcontrib><creatorcontrib>Delgado-Rodríguez, Miguel</creatorcontrib><creatorcontrib>Daimiel, Lidia</creatorcontrib><creatorcontrib>Vázquez, Clotilde</creatorcontrib><creatorcontrib>Rubio, Miguel Ángel</creatorcontrib><creatorcontrib>Ros, Emilio</creatorcontrib><creatorcontrib>Salas-Salvadó, Jordi</creatorcontrib><creatorcontrib>PREDIMED-PLUS investigators</creatorcontrib><title>Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS trial. Employing multivariable-adjusted Cox regression with robust variance and constant time (given the cross-sectional design), higher prevalence of obesity, T2D and abdominal obesity as component of the MetS were associated with greater time in TV-viewing (Relative Risk, RR: 1.02, 95%CI: 1.01, 1.03; RR:1.04, 95%CI: 1.02, 1.06 and RR: 1.01 95%CI: 1.00, 1.02; respectively, all P &lt; .01). Conversely, greater time in moderate-vigorous PA (MVPA) was associated with lower prevalence of obesity, T2D, abdominal obesity and low HDL-cholesterol (RR: 0.95, 95%CI: 0.93, 0.97; RR: 0.94, 95%CI: 0.89, 0.99; RR: 0.97, 95%CI: 0.96, 0.98; and RR: 0.95, 95%CI: 0.91, 0.99, respectively, all P &lt; .05). For these outcomes, theoretically substituting 1-h/day of MVPA for 1-h/day TV-viewing was also significantly associated with lower prevalence (RR 0.91 to 0.97, all P &lt; .05). Similar lower RR in these outcomes was observed when substituting 1-h/day of MVPA for 1-h/day of sleeping. Longer time watching TV and not meeting MVPA recommendations were jointly associated with higher RR of the prevalence of obesity and T2D. We concluded that, in senior individuals at high cardiovascular risk, greater time spent on MVPA and fewer on sedentary behaviors was inversely associated with prevalence of obesity, T2D, and some of the components of MetS.</description><subject>Adults</subject><subject>Aged</subject><subject>Analysis</subject><subject>Biochemistry</subject><subject>Biology and Life Sciences</subject><subject>Biomarkers</subject><subject>Biomedical research</subject><subject>Biotechnology</subject><subject>Body weight</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular Diseases - complications</subject><subject>Cholesterol</subject><subject>Clinical trials</subject><subject>Cross-Sectional Studies</subject><subject>Data processing</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes Mellitus, Type 2 - etiology</subject><subject>Diabetis no-insulinodependent</subject><subject>Disease prevention</subject><subject>Endocrinology</subject><subject>Epidemiologia</subject><subject>Epidemiology</subject><subject>Etiologia</subject><subject>Etiology</subject><subject>Exercise</subject><subject>Factors de risc en les malalties</subject><subject>Female</subject><subject>Health behavior</subject><subject>Health care</subject><subject>Health risks</subject><subject>Health sciences</subject><subject>High density lipoprotein</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hàbits sanitaris</subject><subject>Internal medicine</subject><subject>Internet</subject><subject>Lipids</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine and Health Sciences</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Metabolic Syndrome - etiology</subject><subject>Metabolism</subject><subject>Middle Aged</subject><subject>Non-insulin-dependent diabetes</subject><subject>Nutrition research</subject><subject>Obesity</subject><subject>Odds Ratio</subject><subject>Overweight</subject><subject>Physical activity</subject><subject>Physical fitness</subject><subject>Prevalence</subject><subject>Preventive medicine</subject><subject>Public health</subject><subject>Regression analysis</subject><subject>Risk analysis</subject><subject>Risk Factors</subject><subject>Risk factors in diseases</subject><subject>Risk taking</subject><subject>Robustness (mathematics)</subject><subject>Sedentary Behavior</subject><subject>Sleep</subject><subject>Son</subject><subject>Spain - epidemiology</subject><subject>Systematic review</subject><subject>Síndrome metabòlica</subject><subject>Type 2 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physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis</title><author>Rosique-Esteban, Nuria ; Díaz-López, Andrés ; Martínez-González, Miguel A ; Corella, Dolores ; Goday, Albert ; Martínez, J Alfredo ; Romaguera, Dora ; Vioque, Jesus ; Arós, Fernando ; Garcia-Rios, Antonio ; Tinahones, Francisco ; Estruch, Ramon ; Fernández-García, José Carlos ; Lapetra, José ; Serra-Majem, Luís ; Pinto, Xavier ; Tur, Josep A ; Bueno-Cavanillas, Aurora ; Vidal, Josep ; Delgado-Rodríguez, Miguel ; Daimiel, Lidia ; Vázquez, Clotilde ; Rubio, Miguel Ángel ; Ros, Emilio ; Salas-Salvadó, Jordi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c767t-5f77b20213cb20cdfcff535d5f02219f817c7aa204d6fde499cc4bae63ec47d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adults</topic><topic>Aged</topic><topic>Analysis</topic><topic>Biochemistry</topic><topic>Biology and Life Sciences</topic><topic>Biomarkers</topic><topic>Biomedical research</topic><topic>Biotechnology</topic><topic>Body weight</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular diseases</topic><topic>Cardiovascular Diseases - complications</topic><topic>Cholesterol</topic><topic>Clinical trials</topic><topic>Cross-Sectional Studies</topic><topic>Data processing</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Diabetes mellitus (non-insulin dependent)</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes Mellitus, Type 2 - etiology</topic><topic>Diabetis no-insulinodependent</topic><topic>Disease prevention</topic><topic>Endocrinology</topic><topic>Epidemiologia</topic><topic>Epidemiology</topic><topic>Etiologia</topic><topic>Etiology</topic><topic>Exercise</topic><topic>Factors de risc en les malalties</topic><topic>Female</topic><topic>Health behavior</topic><topic>Health care</topic><topic>Health risks</topic><topic>Health sciences</topic><topic>High density lipoprotein</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hàbits sanitaris</topic><topic>Internal medicine</topic><topic>Internet</topic><topic>Lipids</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine and Health Sciences</topic><topic>Metabolic disorders</topic><topic>Metabolic syndrome</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Metabolic Syndrome - etiology</topic><topic>Metabolism</topic><topic>Middle Aged</topic><topic>Non-insulin-dependent diabetes</topic><topic>Nutrition research</topic><topic>Obesity</topic><topic>Odds Ratio</topic><topic>Overweight</topic><topic>Physical activity</topic><topic>Physical fitness</topic><topic>Prevalence</topic><topic>Preventive medicine</topic><topic>Public health</topic><topic>Regression analysis</topic><topic>Risk analysis</topic><topic>Risk Factors</topic><topic>Risk factors in diseases</topic><topic>Risk taking</topic><topic>Robustness (mathematics)</topic><topic>Sedentary Behavior</topic><topic>Sleep</topic><topic>Son</topic><topic>Spain - epidemiology</topic><topic>Systematic review</topic><topic>Síndrome metabòlica</topic><topic>Type 2 diabetes</topic><topic>Viewing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rosique-Esteban, Nuria</creatorcontrib><creatorcontrib>Díaz-López, Andrés</creatorcontrib><creatorcontrib>Martínez-González, Miguel A</creatorcontrib><creatorcontrib>Corella, Dolores</creatorcontrib><creatorcontrib>Goday, Albert</creatorcontrib><creatorcontrib>Martínez, J Alfredo</creatorcontrib><creatorcontrib>Romaguera, Dora</creatorcontrib><creatorcontrib>Vioque, Jesus</creatorcontrib><creatorcontrib>Arós, Fernando</creatorcontrib><creatorcontrib>Garcia-Rios, Antonio</creatorcontrib><creatorcontrib>Tinahones, Francisco</creatorcontrib><creatorcontrib>Estruch, Ramon</creatorcontrib><creatorcontrib>Fernández-García, José Carlos</creatorcontrib><creatorcontrib>Lapetra, José</creatorcontrib><creatorcontrib>Serra-Majem, Luís</creatorcontrib><creatorcontrib>Pinto, Xavier</creatorcontrib><creatorcontrib>Tur, Josep A</creatorcontrib><creatorcontrib>Bueno-Cavanillas, Aurora</creatorcontrib><creatorcontrib>Vidal, Josep</creatorcontrib><creatorcontrib>Delgado-Rodríguez, Miguel</creatorcontrib><creatorcontrib>Daimiel, Lidia</creatorcontrib><creatorcontrib>Vázquez, Clotilde</creatorcontrib><creatorcontrib>Rubio, Miguel Ángel</creatorcontrib><creatorcontrib>Ros, Emilio</creatorcontrib><creatorcontrib>Salas-Salvadó, Jordi</creatorcontrib><creatorcontrib>PREDIMED-PLUS investigators</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological &amp; Geoastrophysical Abstracts</collection><collection>Nucleic 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&amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Recercat</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rosique-Esteban, Nuria</au><au>Díaz-López, Andrés</au><au>Martínez-González, Miguel A</au><au>Corella, Dolores</au><au>Goday, Albert</au><au>Martínez, J Alfredo</au><au>Romaguera, Dora</au><au>Vioque, Jesus</au><au>Arós, Fernando</au><au>Garcia-Rios, Antonio</au><au>Tinahones, Francisco</au><au>Estruch, Ramon</au><au>Fernández-García, José Carlos</au><au>Lapetra, José</au><au>Serra-Majem, Luís</au><au>Pinto, Xavier</au><au>Tur, Josep A</au><au>Bueno-Cavanillas, Aurora</au><au>Vidal, Josep</au><au>Delgado-Rodríguez, Miguel</au><au>Daimiel, Lidia</au><au>Vázquez, Clotilde</au><au>Rubio, Miguel Ángel</au><au>Ros, Emilio</au><au>Salas-Salvadó, Jordi</au><aucorp>PREDIMED-PLUS investigators</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-03-08</date><risdate>2017</risdate><volume>12</volume><issue>3</issue><spage>e0172253</spage><epage>e0172253</epage><pages>e0172253-e0172253</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS trial. Employing multivariable-adjusted Cox regression with robust variance and constant time (given the cross-sectional design), higher prevalence of obesity, T2D and abdominal obesity as component of the MetS were associated with greater time in TV-viewing (Relative Risk, RR: 1.02, 95%CI: 1.01, 1.03; RR:1.04, 95%CI: 1.02, 1.06 and RR: 1.01 95%CI: 1.00, 1.02; respectively, all P &lt; .01). Conversely, greater time in moderate-vigorous PA (MVPA) was associated with lower prevalence of obesity, T2D, abdominal obesity and low HDL-cholesterol (RR: 0.95, 95%CI: 0.93, 0.97; RR: 0.94, 95%CI: 0.89, 0.99; RR: 0.97, 95%CI: 0.96, 0.98; and RR: 0.95, 95%CI: 0.91, 0.99, respectively, all P &lt; .05). For these outcomes, theoretically substituting 1-h/day of MVPA for 1-h/day TV-viewing was also significantly associated with lower prevalence (RR 0.91 to 0.97, all P &lt; .05). Similar lower RR in these outcomes was observed when substituting 1-h/day of MVPA for 1-h/day of sleeping. Longer time watching TV and not meeting MVPA recommendations were jointly associated with higher RR of the prevalence of obesity and T2D. We concluded that, in senior individuals at high cardiovascular risk, greater time spent on MVPA and fewer on sedentary behaviors was inversely associated with prevalence of obesity, T2D, and some of the components of MetS.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28273154</pmid><doi>10.1371/journal.pone.0172253</doi><tpages>e0172253</tpages><oa>free_for_read</oa></addata></record>
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subjects Adults
Aged
Analysis
Biochemistry
Biology and Life Sciences
Biomarkers
Biomedical research
Biotechnology
Body weight
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - complications
Cholesterol
Clinical trials
Cross-Sectional Studies
Data processing
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - etiology
Diabetis no-insulinodependent
Disease prevention
Endocrinology
Epidemiologia
Epidemiology
Etiologia
Etiology
Exercise
Factors de risc en les malalties
Female
Health behavior
Health care
Health risks
Health sciences
High density lipoprotein
Hospitals
Humans
Hàbits sanitaris
Internal medicine
Internet
Lipids
Male
Medical research
Medicine and Health Sciences
Metabolic disorders
Metabolic syndrome
Metabolic Syndrome - epidemiology
Metabolic Syndrome - etiology
Metabolism
Middle Aged
Non-insulin-dependent diabetes
Nutrition research
Obesity
Odds Ratio
Overweight
Physical activity
Physical fitness
Prevalence
Preventive medicine
Public health
Regression analysis
Risk analysis
Risk Factors
Risk factors in diseases
Risk taking
Robustness (mathematics)
Sedentary Behavior
Sleep
Son
Spain - epidemiology
Systematic review
Síndrome metabòlica
Type 2 diabetes
Viewing
title Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis
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