Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats

Recent data from long-distance endurance participants suggest that cardiac function is impaired after completion. Existing data further indicate that right ventricular function is more affected than left ventricular function. The cellular mechanisms underpinning cardiac deterioration are limited and...

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Veröffentlicht in:	PloS one 2017-03, Vol.12 (3), p.e0173449-e0173449
Hauptverfasser:	Ljones, Kristine, Ness, Henning Ofstad, Solvang-Garten, Karin, Gaustad, Svein Erik, Høydal, Morten Andre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Aerobic exercises Aerobics Animals Bioenergetics Biology and Life Sciences Biomarkers Ca2+-transporting ATPase Calcium Calcium (intracellular) Calcium (mitochondrial) Calcium (reticular) Calcium - metabolism Calcium ions Cardiac muscle Cardiology Cardiomyocytes Cell Membrane Permeability Cell Respiration Cells, Cultured Contraction Diastole Durability Electron transport Endurance Exercise Fitness equipment Handling Heart Heart - physiopathology Heart cells Heart diseases Ion transport Male Medical imaging Medicine Medicine and Health Sciences Mental depression Mitochondria Mitochondria, Heart - metabolism Muscle contraction Muscles Myocardial Contraction Myocardium - metabolism Myocytes, Cardiac - metabolism Observations Oxidative phosphorylation Phospholamban Phosphorylation Physical Conditioning, Animal Physical fitness Physical Sciences Physiological aspects Physiology Properties Pulmonary arteries Rats Rats, Sprague-Dawley Reduction Rehabilitation Research and Analysis Methods Respiration Rodents Running Sarcoplasmic reticulum Science Serine Studies Threonine Ventricle Working groups Workloads
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