Meta-analyses of comparative efficacy of antidepressant medications on peripheral BDNF concentration in patients with depression

Brain derived neurotrophic factor (BDNF) is one of the most important regulatory proteins in the pathophysiology of major depressive disorder (MDD). Increasing numbers of studies have reported the relationship between serum/plasma BDNF and antidepressants (ADs). However, the potential effects of sev...

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Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0172270-e0172270
Hauptverfasser:	Zhou, Chanjuan, Zhong, Jiaju, Zou, Bin, Fang, Liang, Chen, Jianjun, Deng, Xiao, Zhang, Lin, Zhao, Xiang, Qu, Zehui, Lei, Yang, Lei, Ting
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antidepressants Antidepressive Agents - therapeutic use Biology and Life Sciences Blood Brain Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - blood Care and treatment Citalopram Citalopram - therapeutic use Clinical trials Clinical Trials as Topic Confidence intervals Data Interpretation, Statistical Depression (Mood disorder) Depression - blood Depression - drug therapy Dosage and administration Drugs Heterogeneity Humans Medical ethics Medicine and Health Sciences Mental depression Meta-analysis Paroxetine Paroxetine - therapeutic use Peripheral blood Pharmacology Physical Sciences Proteins Psychological aspects Regulatory proteins Reproducibility of Results Research and Analysis Methods Rodents Sensitivity and Specificity Sertraline Sertraline - therapeutic use Statistical analysis Statistical methods Statistical tests Studies Treatment outcome Venlafaxine Venlafaxine Hydrochloride - therapeutic use
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