Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy

Lung cancer is one of the most common malignancies with a high rate of mortality. Lung cancer stem-like cells (CSCs)/ cancer-initiating cells (CICs) play major role in resistance to treatments, recurrence and distant metastasis and eradication of CSCs/CICs is crucial to improve recent therapy. Cytot...

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Veröffentlicht in:	PloS one 2017-03, Vol.12 (3), p.e0171460-e0171460
Hauptverfasser:	Horibe, Ryota, Hirohashi, Yoshihiko, Asano, Takuya, Mariya, Tasuku, Suzuki, Takeshi, Takaya, Akari, Saijo, Hiroshi, Shionoya, Yosuke, Kubo, Terufumi, Nakatsugawa, Munehide, Kanaseki, Takayuki, Tsukahara, Tomohide, Watanabe, Kazue, Atsuyama, Eri, Toji, Shingo, Hirano, Hiroshi, Hasegawa, Tadashi, Takahashi, Hiroki, Sato, Noriyuki, Torigoe, Toshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Antigens, Neoplasm - genetics Antigens, Neoplasm - immunology Biology and Life Sciences Cancer Cancer cells Cancer immunotherapy Cancer therapies Care and treatment Chemotherapy Cytotoxicity DNA methylation DNA-Binding Proteins - genetics DNA-Binding Proteins - immunology Eradication Female Gene expression Genetic aspects Gynecology Histocompatibility antigen HLA HLA-A2 Antigen - genetics HLA-A2 Antigen - immunology Humans Immunotherapy Immunotherapy - methods K562 Cells Laboratories Leukocytes Lung cancer Lung carcinoma Lung diseases Lung Neoplasms - genetics Lung Neoplasms - immunology Lung Neoplasms - pathology Lung Neoplasms - therapy Lymphocytes Lymphocytes T Major histocompatibility complex Male Medical prognosis Medical research Medicine Medicine and Health Sciences Metastases Metastasis mRNA Neoplasm Proteins - genetics Neoplasm Proteins - immunology Neoplastic Stem Cells - immunology Neoplastic Stem Cells - pathology Obstetrics Pathology Peptides Peptides - genetics Peptides - immunology Physicians Polymerase chain reaction Radiation therapy Research and Analysis Methods Tissues
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