The gene expression of the neuronal protein, SLC38A9, changes in mouse brain after in vivo starvation and high-fat diet

SLC38A9 is characterized as a lysosomal component of the amino acid sensing Ragulator-RAG GTPase complex, controlling the mechanistic target of rapamycin complex 1 (mTORC1). Here, immunohistochemistry was used to map SLC38A9 in mouse brain and staining was detected throughout the brain, in cortex, h...

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Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0172917-e0172917
Hauptverfasser:	Hellsten, Sofie V, Eriksson, Mikaela M, Lekholm, Emilia, Arapi, Vasiliki, Perland, Emelie, Fredriksson, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Amino Acid Transport Systems - genetics Amino Acid Transport Systems - metabolism Amino acids Analysis Animals Astrocytes Biology and Life Sciences Brain Brain - metabolism Brain mapping Brain research Brain stem Cell cycle Cell growth Cerebellum Chemoreception Cortex (piriform) Diet Diet, High-Fat Endocrinology Gene Expression Glutamatergic transmission Guanosine triphosphatases High fat diet Homeostasis Homogenization Hypothalamus Hypothalamus - metabolism Immunohistochemistry In vivo methods and tests Kinases Male Medicine and Health Sciences Metabolism Mice, Inbred C57BL Pharmaceuticals Physiology Piriform cortex Proteins Rapamycin Research and Analysis Methods Rodents Signaling Starvation - metabolism Thalamus Tissues TOR protein Up-Regulation γ-Aminobutyric acid
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