E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine

Extracellular adenosine 5'-triphosphate (ATP) performs multiple functions including activation and induction of apoptosis of many cell types. The ATP-hydrolyzing ectoenzyme ecto-nucleotide pyrophosphatase/phosphodiesterase 3 (E-NPP3) regulates ATP-dependent chronic allergic responses by mast ce...

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Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0172509-e0172509
Hauptverfasser:	Furuta, Yoki, Tsai, Shih-Han, Kinoshita, Makoto, Fujimoto, Kosuke, Okumura, Ryu, Umemoto, Eiji, Kurashima, Yosuke, Kiyono, Hiroshi, Kayama, Hisako, Takeda, Kiyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Adenosine triphosphate Adenosine Triphosphate - metabolism Animals Annexin V Apoptosis ATP B cells Biology and Life Sciences Caspase Caspase 3 - metabolism Caspase-3 Cell death Cell Death - physiology Dendritic cells Dendritic Cells - metabolism Epithelial cells Hepatitis Hypersensitivity Immunology Infections Inflammation Interferon Intestinal Mucosa - cytology Intestinal Mucosa - metabolism Intestine, Small - cytology Intestine, Small - metabolism Laboratories Lamina propria Leukocytes (basophilic) Lymphatic system Mast cells Medical research Medicine Medicine and Health Sciences Mice Mice, Knockout Mortality Peyer's Patches - metabolism Phosphodiesterase Phosphoric Diester Hydrolases - genetics Phosphoric Diester Hydrolases - metabolism Pyrophosphatase Pyrophosphatases - genetics Pyrophosphatases - metabolism R&D Research & development Research and Analysis Methods Rodents Science Small intestine Statistics T cell receptors Viral infections
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