The distinct features of microbial 'dysbiosis' of Crohn's disease do not occur to the same extent in their unaffected, genetically-linked kindred

Studying the gut microbiota in unaffected relatives of people with Crohn's disease (CD) may advance our understanding of the role of bacteria in disease aetiology. Faecal microbiota composition (16S rRNA gene sequencing), genetic functional capacity (shotgun metagenomics) and faecal short chain...

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Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0172605-e0172605
Hauptverfasser:	Ijaz, Umer Zeeshan, Quince, Christopher, Hanske, Laura, Loman, Nick, Calus, Szymon T, Bertz, Martin, Edwards, Christine A, Gaya, Daniel R, Hansen, Richard, McGrogan, Paraic, Russell, Richard K, Gerasimidis, Konstantinos
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bacteria Bacteria - genetics Bacteria - isolation & purification Bacteria - metabolism Biodiversity Bioinformatics Biology Biology and Life Sciences Care and treatment Child Children Communities Community structure Comparative analysis Crohn Disease - genetics Crohn Disease - microbiology Crohn's disease Dentistry Disease Dysbacteriosis Dysbiosis - etiology Dysbiosis - genetics Dysbiosis - microbiology Family Health Fatty acids Fatty Acids, Volatile - analysis Feces - chemistry Feces - microbiology Female Gastroenterology Gastrointestinal Microbiome Gene sequencing Genes Genetic aspects Health aspects Hepatology Hospitals Humans Intestinal microflora Leukocyte L1 Antigen Complex - analysis Life sciences Male Medicine Medicine and Health Sciences Metabolic Networks and Pathways Metabolic pathways Metagenomics Microbiota Microbiota (Symbiotic organisms) Microorganisms Nursing Nutrition Parents Patients Research and analysis methods Ribotyping RNA rRNA 16S Siblings Studies
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