Autophagy Is an Innate Mechanism Associated with Leprosy Polarization

Leprosy is a chronic infectious disease that may present different clinical forms according to the immune response of the host. Levels of IFN-γ are significantly raised in paucibacillary tuberculoid (T-lep) when compared with multibacillary lepromatous (L-lep) patients. IFN-γ primes macrophages for...

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Veröffentlicht in:	PLoS pathogens 2017-01, Vol.13 (1), p.e1006103-e1006103
Hauptverfasser:	Silva, Bruno Jorge de Andrade, Barbosa, Mayara Garcia de Mattos, Andrade, Priscila Ribeiro, Ferreira, Helen, Nery, José Augusto da Costa, Côrte-Real, Suzana, da Silva, Gilberto Marcelo Sperandio, Rosa, Patricia Sammarco, Fabri, Mario, Sarno, Euzenir Nunes, Pinheiro, Roberta Olmo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis Autophagy Autophagy (Cytology) Autophagy - physiology Biology and Life Sciences Blotting, Western Colleges & universities Enzyme-Linked Immunosorbent Assay Experiments Female Fluorescent Antibody Technique Funding Gene expression Humans Immune response Immunity (Physiology) Immunohistochemistry Infectious diseases Interferon-gamma - immunology Laboratory animals Leprosy Leprosy - immunology Leprosy - pathology Macrophages - immunology Male Medicine and Health Sciences Microscopy, Electron, Transmission Middle Aged Mycobacterium leprae Mycobacterium leprae - immunology Peptides Polymerase Chain Reaction Risk factors Skin - immunology Skin - microbiology Skin - pathology Software Transcriptome Young Adult
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