Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction

The mammalian Y chromosome plays a critical role in spermatogenesis. However, the exact functions of each gene in the Y chromosome have not been completely elucidated, partly owing to difficulties in gene targeting analysis of the Y chromosome. Zfy was first proposed to be a sex determination factor...

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Veröffentlicht in:	PLoS genetics 2017-01, Vol.13 (1), p.e1006578
Hauptverfasser:	Nakasuji, Takashi, Ogonuki, Narumi, Chiba, Tomoki, Kato, Tomomi, Shiozawa, Kumiko, Yamatoya, Kenji, Tanaka, Hiromitsu, Kondo, Tadashi, Miyado, Kenji, Miyasaka, Naoyuki, Kubota, Toshiro, Ogura, Atsuo, Asahara, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Biology and Life Sciences Chromosomes DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Embryonic development Fertilization - genetics Gene Deletion Genes GPI-Linked Proteins - genetics GPI-Linked Proteins - metabolism Huntingtin Protein - genetics Huntingtin Protein - metabolism Infertility Male Medicine and Health Sciences Mice Phosphoinositide Phospholipase C - genetics Phosphoinositide Phospholipase C - metabolism Phospholipase C delta - genetics Phospholipase C delta - metabolism Physiological aspects Rodents Serine Endopeptidases - genetics Serine Endopeptidases - metabolism Spermatogenesis - genetics Transcription Factors - genetics Transcription Factors - metabolism Y Chromosome - genetics
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