MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke

Ischemic stroke is a major cause of mortality and morbidity globally. Among the ischemic stroke subtypes, cardioembolic stroke is with poor functional outcome (Modified Rankin score ≥ 2). Early diagnosis of cardioembolic stroke will prove beneficial. This study examined the microRNAs targeting clust...

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Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0172131-e0172131
Hauptverfasser:	Tan, Jun Rong, Tan, Kay Sin, Yong, Fung Lin, Armugam, Arunmozhiarasi, Wang, Chee Woon, Jeyaseelan, Kandiah, Wong, Peter Tsun-Hon
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Adult Aged Aged, 80 and over Analysis Apoptosis Area Under Curve Base Sequence Biochemistry Biology and life sciences Biomarkers Case-Control Studies CD46 antigen Cell differentiation Clusters Diagnosis Differentiation Endothelial cells Female Gene expression Genes, Reporter Health aspects Homeostasis Human Umbilical Vein Endothelial Cells Humans Ischemia Kinases Luciferase Male Medicine Medicine and Health Sciences Membrane Cofactor Protein - chemistry Membrane Cofactor Protein - genetics Membrane Cofactor Protein - metabolism MicroRNA MicroRNAs MicroRNAs - chemistry MicroRNAs - genetics MicroRNAs - metabolism Middle Aged miRNA Morbidity mRNA NMR Nuclear magnetic resonance Pathogenesis Patients ROC Curve Sequence Alignment Stroke Stroke - genetics Stroke - pathology Umbilical vein
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