The SLC6A3 gene possibly affects susceptibility to late-onset alcohol dependence but not specific personality traits in a Han Chinese population

Dopaminergic dysfunction has an important role in the pathoetiology of alcohol dependence (AD). The purpose of this study was to determine whether the solute carrier family 6 member 3 (SLC6A3) gene (also known as the dopamine transporter DAT gene) was associated with AD, and whether variants in the...

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Veröffentlicht in:	PloS one 2017-02, Vol.12 (2), p.e0171170
Hauptverfasser:	Huang, Chang-Chih, Kuo, Shin-Chang, Yeh, Yi-Wei, Chen, Chun-Yen, Yen, Che-Hung, Liang, Chih-Sung, Ho, Pei-Shen, Lu, Ru-Band, Huang, San-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Age of Onset Alcohol use Alcoholic beverages Alcoholism Alcoholism - genetics Alcohols Alleles Analysis Biology and Life Sciences Brain research Case-Control Studies China Disease susceptibility Dopamine Dopamine Plasma Membrane Transport Proteins - genetics Dopamine receptors Dopamine transporter Drug dependence Exploratory Behavior Female Gene expression Gene frequency Genotypes Han (Chinese people) Health aspects Heterozygote Hospitals Humans Male Medicine and Health Sciences Mental depression Middle Aged Patients People and places Personality Personality traits Polymorphism, Single Nucleotide Population Psychiatry Regression analysis Risk factors Risk-Taking Social Sciences Studies Subgroups Transporter
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