Association between tooth loss and cognitive decline: A 13-year longitudinal study of Chinese older adults
To examine the association between the number of teeth remaining and cognitive decline among Chinese older adults over a 13-year period. A large national longitudinal survey of Chinese older adults. The Chinese Longitudinal Healthy Longevity Survey (CLHLS) (1998-2011). A total of 8,153 eligible part...
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description | To examine the association between the number of teeth remaining and cognitive decline among Chinese older adults over a 13-year period.
A large national longitudinal survey of Chinese older adults.
The Chinese Longitudinal Healthy Longevity Survey (CLHLS) (1998-2011).
A total of 8,153 eligible participants aged 60+ interviewed in up to six waves.
Cognitive function and teeth number were measured at each interview. Cognitive function was measured by the Mini-Mental Status Examination (MMSE). Number of natural teeth was self-reported. Individuals with severe cognitive impairment were excluded. Covariates included demographic characteristics, adult socioeconomic status characteristics, childhood socioeconomic status, health conditions, and health behaviors. Linear mixed models were applied in the analysis.
The mean teeth number at baseline was 17.5(SD = 0.1), and the mean of baseline cognitive function was 27.3(SD = 0.0). Cognitive function declined over time (β = -0.19, P < .001) after controlling covariates. But, regardless of time, more teeth were associated with better cognitive function (β = 0.01, P < .001). The interaction of teeth number and time was significant (β = 0.01, P < .001), suggesting that the participants who had more teeth showed a slower pace of cognitive decline over time than those with fewer teeth after controlling for other covariates.
This study showed that tooth loss was associated with cognitive decline among Chinese older adults. Further studies are needed to examine the linkages between cognitive decline and oral health status using clinical examination data. |
doi_str_mv | 10.1371/journal.pone.0171404 |
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A large national longitudinal survey of Chinese older adults.
The Chinese Longitudinal Healthy Longevity Survey (CLHLS) (1998-2011).
A total of 8,153 eligible participants aged 60+ interviewed in up to six waves.
Cognitive function and teeth number were measured at each interview. Cognitive function was measured by the Mini-Mental Status Examination (MMSE). Number of natural teeth was self-reported. Individuals with severe cognitive impairment were excluded. Covariates included demographic characteristics, adult socioeconomic status characteristics, childhood socioeconomic status, health conditions, and health behaviors. Linear mixed models were applied in the analysis.
The mean teeth number at baseline was 17.5(SD = 0.1), and the mean of baseline cognitive function was 27.3(SD = 0.0). Cognitive function declined over time (β = -0.19, P < .001) after controlling covariates. But, regardless of time, more teeth were associated with better cognitive function (β = 0.01, P < .001). The interaction of teeth number and time was significant (β = 0.01, P < .001), suggesting that the participants who had more teeth showed a slower pace of cognitive decline over time than those with fewer teeth after controlling for other covariates.
This study showed that tooth loss was associated with cognitive decline among Chinese older adults. Further studies are needed to examine the linkages between cognitive decline and oral health status using clinical examination data.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0171404</identifier><identifier>PMID: 28158261</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Adults ; Aged ; Aged, 80 and over ; Analysis ; Asian Continental Ancestry Group - statistics & numerical data ; Biology and Life Sciences ; Care and treatment ; Children ; Cognition - physiology ; Cognitive ability ; Cognitive Dysfunction - epidemiology ; Correlation analysis ; Dementia ; Demographics ; Female ; Health behavior ; Health risk assessment ; Humans ; Linear Models ; Longitudinal Studies ; Male ; Medicine and Health Sciences ; Models, Theoretical ; Older people ; People and Places ; Risk factors ; Social Class ; Socioeconomic factors ; Socioeconomics ; Studies ; Surveys ; Teeth ; Tooth loss ; Tooth Loss - epidemiology</subject><ispartof>PloS one, 2017-02, Vol.12 (2), p.e0171404-e0171404</ispartof><rights>COPYRIGHT 2017 Public Library of Science</rights><rights>2017 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2017 Li et al 2017 Li et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c791t-89bfb0a2f53fb5a40031b53e9c194cf617261c42c56a50aa43bd5b9f580890923</citedby><cites>FETCH-LOGICAL-c791t-89bfb0a2f53fb5a40031b53e9c194cf617261c42c56a50aa43bd5b9f580890923</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291434/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291434/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793,79600,79601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28158261$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Brucki, Sonia</contributor><creatorcontrib>Li, Juan</creatorcontrib><creatorcontrib>Xu, Hanzhang</creatorcontrib><creatorcontrib>Pan, Wei</creatorcontrib><creatorcontrib>Wu, Bei</creatorcontrib><title>Association between tooth loss and cognitive decline: A 13-year longitudinal study of Chinese older adults</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>To examine the association between the number of teeth remaining and cognitive decline among Chinese older adults over a 13-year period.
A large national longitudinal survey of Chinese older adults.
The Chinese Longitudinal Healthy Longevity Survey (CLHLS) (1998-2011).
A total of 8,153 eligible participants aged 60+ interviewed in up to six waves.
Cognitive function and teeth number were measured at each interview. Cognitive function was measured by the Mini-Mental Status Examination (MMSE). Number of natural teeth was self-reported. Individuals with severe cognitive impairment were excluded. Covariates included demographic characteristics, adult socioeconomic status characteristics, childhood socioeconomic status, health conditions, and health behaviors. Linear mixed models were applied in the analysis.
The mean teeth number at baseline was 17.5(SD = 0.1), and the mean of baseline cognitive function was 27.3(SD = 0.0). Cognitive function declined over time (β = -0.19, P < .001) after controlling covariates. But, regardless of time, more teeth were associated with better cognitive function (β = 0.01, P < .001). The interaction of teeth number and time was significant (β = 0.01, P < .001), suggesting that the participants who had more teeth showed a slower pace of cognitive decline over time than those with fewer teeth after controlling for other covariates.
This study showed that tooth loss was associated with cognitive decline among Chinese older adults. Further studies are needed to examine the linkages between cognitive decline and oral health status using clinical examination data.</description><subject>Adults</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Analysis</subject><subject>Asian Continental Ancestry Group - statistics & numerical data</subject><subject>Biology and Life Sciences</subject><subject>Care and treatment</subject><subject>Children</subject><subject>Cognition - physiology</subject><subject>Cognitive ability</subject><subject>Cognitive Dysfunction - epidemiology</subject><subject>Correlation analysis</subject><subject>Dementia</subject><subject>Demographics</subject><subject>Female</subject><subject>Health behavior</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Linear Models</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Medicine and Health Sciences</subject><subject>Models, Theoretical</subject><subject>Older people</subject><subject>People and Places</subject><subject>Risk factors</subject><subject>Social Class</subject><subject>Socioeconomic factors</subject><subject>Socioeconomics</subject><subject>Studies</subject><subject>Surveys</subject><subject>Teeth</subject><subject>Tooth loss</subject><subject>Tooth Loss - 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statistics & numerical data</topic><topic>Biology and Life Sciences</topic><topic>Care and treatment</topic><topic>Children</topic><topic>Cognition - physiology</topic><topic>Cognitive ability</topic><topic>Cognitive Dysfunction - epidemiology</topic><topic>Correlation analysis</topic><topic>Dementia</topic><topic>Demographics</topic><topic>Female</topic><topic>Health behavior</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Linear Models</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Medicine and Health Sciences</topic><topic>Models, Theoretical</topic><topic>Older people</topic><topic>People and Places</topic><topic>Risk factors</topic><topic>Social Class</topic><topic>Socioeconomic factors</topic><topic>Socioeconomics</topic><topic>Studies</topic><topic>Surveys</topic><topic>Teeth</topic><topic>Tooth loss</topic><topic>Tooth Loss - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Juan</creatorcontrib><creatorcontrib>Xu, Hanzhang</creatorcontrib><creatorcontrib>Pan, Wei</creatorcontrib><creatorcontrib>Wu, Bei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Juan</au><au>Xu, Hanzhang</au><au>Pan, Wei</au><au>Wu, Bei</au><au>Brucki, Sonia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between tooth loss and cognitive decline: A 13-year longitudinal study of Chinese older adults</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2017-02-03</date><risdate>2017</risdate><volume>12</volume><issue>2</issue><spage>e0171404</spage><epage>e0171404</epage><pages>e0171404-e0171404</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>To examine the association between the number of teeth remaining and cognitive decline among Chinese older adults over a 13-year period.
A large national longitudinal survey of Chinese older adults.
The Chinese Longitudinal Healthy Longevity Survey (CLHLS) (1998-2011).
A total of 8,153 eligible participants aged 60+ interviewed in up to six waves.
Cognitive function and teeth number were measured at each interview. Cognitive function was measured by the Mini-Mental Status Examination (MMSE). Number of natural teeth was self-reported. Individuals with severe cognitive impairment were excluded. Covariates included demographic characteristics, adult socioeconomic status characteristics, childhood socioeconomic status, health conditions, and health behaviors. Linear mixed models were applied in the analysis.
The mean teeth number at baseline was 17.5(SD = 0.1), and the mean of baseline cognitive function was 27.3(SD = 0.0). Cognitive function declined over time (β = -0.19, P < .001) after controlling covariates. But, regardless of time, more teeth were associated with better cognitive function (β = 0.01, P < .001). The interaction of teeth number and time was significant (β = 0.01, P < .001), suggesting that the participants who had more teeth showed a slower pace of cognitive decline over time than those with fewer teeth after controlling for other covariates.
This study showed that tooth loss was associated with cognitive decline among Chinese older adults. Further studies are needed to examine the linkages between cognitive decline and oral health status using clinical examination data.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>28158261</pmid><doi>10.1371/journal.pone.0171404</doi><tpages>e0171404</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adults Aged Aged, 80 and over Analysis Asian Continental Ancestry Group - statistics & numerical data Biology and Life Sciences Care and treatment Children Cognition - physiology Cognitive ability Cognitive Dysfunction - epidemiology Correlation analysis Dementia Demographics Female Health behavior Health risk assessment Humans Linear Models Longitudinal Studies Male Medicine and Health Sciences Models, Theoretical Older people People and Places Risk factors Social Class Socioeconomic factors Socioeconomics Studies Surveys Teeth Tooth loss Tooth Loss - epidemiology |
title | Association between tooth loss and cognitive decline: A 13-year longitudinal study of Chinese older adults |
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