Association of the Endothelial Nitric Oxide Synthase Gene T786C Polymorphism with In-Stent Restenosis in Chinese Han Patients with Coronary Artery Disease Treated with Drug-Eluting Stent

Many studies have reported that genetic variants correlate with higher risk for coronary artery disease (CAD) or in-stent restenosis (ISR) after bare metal stent (BMS) implantation. However, there is limited data assessing the impact of these variants on ISR in patients treated with drug-eluting ste...

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Veröffentlicht in:	PloS one 2017-01, Vol.12 (1), p.e0170964-e0170964
Hauptverfasser:	Zeng, Wen-Ping, Zhang, Rui, Li, Ran, Luo, Jin-Fang, Hu, Xiao-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alcohol Angiography Angioplasty Angiotensin Angiotensin II Arteries Atherosclerosis Biology and Life Sciences Cardiology Cardiovascular disease Care and treatment Cell adhesion & migration Confidence intervals Coronary artery Coronary artery disease Coronary Artery Disease - genetics Coronary Artery Disease - pathology Coronary Artery Disease - surgery Coronary heart disease Coronary Restenosis - genetics Coronary Restenosis - pathology Coronary Restenosis - surgery Coronary vessels Diabetes Drug delivery Drug-eluting stents Drug-Eluting Stents - adverse effects Enzymes Family medical history Female Gene polymorphism Genes Genetic aspects Genetic Association Studies Genetic diversity Genetic polymorphisms Genetic Predisposition to Disease Genetic variance Genotype Genotypes Genotyping Growth factors Han (Chinese people) Health aspects Health risk assessment Health risks Heart attacks Heart diseases Humans Implantation Implants Male Medical imaging Medical treatment Medicine and Health Sciences Middle Aged Nitric oxide Nitric Oxide Synthase - genetics Nitric-oxide synthase Patients Peptidyl-dipeptidase A Polymorphism Polymorphism, Single Nucleotide Regression analysis Regression models Research and Analysis Methods Restenosis Risk analysis Risk Factors Rodents Single-nucleotide polymorphism Smoking Smooth muscle Statistical analysis Stents Stents - adverse effects Surgical implants Transforming growth factor-b Vascular endothelial growth factor
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