PACAP Protects Adult Neural Stem Cells from the Neurotoxic Effect of Ketamine Associated with Decreased Apoptosis, ER Stress and mTOR Pathway Activation

Ketamine administration is a well-established approach to mimic experimentally some aspects of schizophrenia. Adult neurogenesis dysregulation is associated with psychiatric disorders, including schizophrenia. The potential role of neurogenesis in the ketamine-induced phenotype is largely unknown. R...

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Veröffentlicht in:PloS one 2017, Vol.12 (1), p.e0170496
Hauptverfasser: Mansouri, Shiva, Agartz, Ingrid, Ögren, Sven-Ove, Patrone, Cesare, Lundberg, Mathias
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Sprache:eng
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