Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System

In this work we set to develop and to validate a new in vivo frameless orthotopic Diffuse Intrinsic Pontine Glioma (DIPG) model based in the implantation of a guide-screw system. It consisted of a guide-screw also called bolt, a Hamilton syringe with a 26-gauge needle and an insulin-like 15-gauge ne...

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Veröffentlicht in:	PloS one 2017-01, Vol.12 (1), p.e0170501-e0170501
Hauptverfasser:	Marigil, Miguel, Martinez-Velez, Naiara, Domínguez, Pablo D, Idoate, Miguel Angel, Xipell, Enric, Patiño-García, Ana, Gonzalez-Huarriz, Marisol, García-Moure, Marc, Junier, Marie-Pierre, Chneiweiss, Hervé, El-Habr, Elías, Diez-Valle, Ricardo, Tejada-Solís, Sonia, Alonso, Marta M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Biology and Life Sciences Biomarkers Brain cancer Brain research Brain Stem Brain Stem Neoplasms - etiology Brain tumors Care and treatment Cell Line, Tumor Chemotherapy Disease Models, Animal Dosage and administration Gene therapy Glioma Glioma - etiology Hospitals Human health and pathology Immunodeficiency Implantation Insertion Insulin Life Sciences Medical research Medicine and Health Sciences Mice Mice, Nude Needles Neoplasm Transplantation - methods Neoplasms, Experimental Neurosciences Neurosurgery Pediatrics Pons Research and Analysis Methods Skull Studies Surgical implants Tumorigenicity Tumors
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