Metabolic Dysregulation in Hepacivirus Infection of Common Marmosets (Callithrix jacchus)

Chronic hepatitis C has been associated with metabolic syndrome that includes insulin resistance, hepatic steatosis and obesity. These metabolic aberrations are risk factors for disease severity and treatment outcome in infected patients. Experimental infection of marmosets with GBV-B serves as a ta...

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Veröffentlicht in:	PloS one 2017-01, Vol.12 (1), p.e0170240
Hauptverfasser:	Manickam, Cordelia, Wachtman, Lynn, Martinot, Amanda J, Giavedoni, Luis D, Reeves, R Keith
Format:	Artikel
Sprache:	eng
Schlagworte:	Aberration Abnormalities Animals Arteriosclerosis Atherosclerosis Biology and life sciences Biomedical research Blood Glucose Body weight loss Callithrix - metabolism Callithrix - virology Callithrix jacchus Cardiovascular disease Care and treatment Chronic infection Complications Complications and side effects Development and progression Diabetes Diabetes mellitus Experimental infection Fatty liver Female Gene expression Glucagon Glucagon - blood Glucagon-like peptide 1 Glucagon-Like Peptide 1 - blood Health risks Hepatitis Hepatitis C Hepatitis C virus Hepatitis C, Chronic - complications Hepatitis C, Chronic - metabolism Immunization Immunology Infections Insulin Insulin - blood Insulin resistance Kidney diseases Laboratory animals Lipid Metabolism Lipids Liver Liver - metabolism Liver cancer Liver diseases Lymphopenia Male Medical treatment Medicine and health sciences Metabolic diseases Metabolic Diseases - complications Metabolic Diseases - virology Metabolic syndrome Mortality Obesity Patients Plasminogen activator inhibitors Prognosis Proteins Research and Analysis Methods Risk analysis Risk factors Rodents Steatosis Thromboembolism Thrombosis Vaccines Viral infections Virology Viruses
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