Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline

Ciliopathies represent a broad class of disorders that affect multiple organ systems. The craniofacial complex is among those most severely affected when primary cilia are not functional. We previously reported that loss of primary cilia on cranial neural crest cells, via a conditional knockout of t...

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Veröffentlicht in:PLoS genetics 2016-11, Vol.12 (11), p.e1006351-e1006351
Hauptverfasser: Chang, Ching-Fang, Chang, Ya-Ting, Millington, Grethel, Brugmann, Samantha A
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Sprache:eng
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