The Role of DNA Methylation and Histone Modifications in Neurodegenerative Diseases: A Systematic Review

Epigenetic modifications of the genome, such as DNA methylation and histone modifications, have been reported to play a role in neurodegenerative diseases (ND) such as Alzheimer's disease (AD) and Parkinson's disease (PD). To systematically review studies investigating epigenetic marks in...

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Veröffentlicht in:	PloS one 2016-12, Vol.11 (12), p.e0167201-e0167201
Hauptverfasser:	Wen, Ke-Xin, Miliç, Jelena, El-Khodor, Bassem, Dhana, Klodian, Nano, Jana, Pulido, Tammy, Kraja, Bledar, Zaciragic, Asija, Bramer, Wichor M, Troup, John, Chowdhury, Rajiv, Ikram, M Arfam, Dehghan, Abbas, Muka, Taulant, Franco, Oscar H
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer's disease Apoptosis Bias Biology and life sciences Brain Brain-derived neurotrophic factor Care and treatment Cell interactions Chromatin Correlation analysis Cross-Sectional Studies Data collection Deoxyribonucleic acid DNA DNA Methylation Epidemiology Epigenesis, Genetic Epigenetic inheritance Epigenetics Gene expression Gene regulation Genes Genome, Human Genomes Histone Code Histones - chemistry Humans Inflammation Longitudinal studies Medicine and Health Sciences Methylation Movement disorders Neurodegenerative diseases Neurodegenerative Diseases - genetics Neurogenesis Neurological diseases Parkinson Disease - genetics Parkinson's disease Randomized Controlled Trials as Topic Reviews Scientific papers Search engines Synuclein
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