TLR-2 Recognizes Propionibacterium acnes CAMP Factor 1 from Highly Inflammatory Strains

Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacteria encountered in inflammatory acne lesions, particularly in the pilosebaceous follicle. P. acnes triggers a strong immune response involving keratinocytes, sebocytes and monocytes, the target cells during acne development. Lipo...

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Veröffentlicht in:	PloS one 2016-11, Vol.11 (11), p.e0167237-e0167237
Hauptverfasser:	Lheure, Coralie, Grange, Philippe Alain, Ollagnier, Guillaume, Morand, Philippe, Désiré, Nathalie, Sayon, Sophie, Corvec, Stéphane, Raingeaud, Jöel, Marcelin, Anne-Geneviève, Calvez, Vincent, Khammari, Amir, Batteux, Frédéric, Dréno, Brigitte, Dupin, Nicolas
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Acne Actinomycetes Amino Acid Sequence Amino acids Antibodies Bacteria Bacterial proteins Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Binding Biology and Life Sciences Cell Line Gene polymorphism Genetic aspects Genomics Gram-positive bacteria Health aspects Humans Immune response Immune system Infections Inflammation Inflammation - microbiology Interleukin-8 - biosynthesis Keratinocytes Lesions Lithium Medicine and Health Sciences Monocytes mRNA Nucleotide sequence Pathogens Peptidoglycans Phylogenetics Phylogeny Polymorphism Polymorphism, Genetic Propionibacterium acnes Propionibacterium acnes - metabolism Propionibacterium acnes - physiology Protein Binding Proteins Receptors Research and Analysis Methods Skin Species Specificity Strains (organisms) Syphilis TLR2 protein Toll-Like Receptor 2 - metabolism Toll-like receptors Transcription Transplants & implants Virulence Virulence (Microbiology) Western blotting
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