Proteomic Profiling for Identification of Novel Biomarkers Differentially Expressed in Human Ovaries from Polycystic Ovary Syndrome Patients

To identify differential protein expression pattern associated with polycystic ovary syndrome (PCOS). Twenty women were recruited for the study, ten with PCOS as a test group and ten without PCOS as a control group. Differential in-gel electrophoresis (DIGE) analysis and mass spectroscopy were emplo...

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Veröffentlicht in:	PloS one 2016-11, Vol.11 (11), p.e0164538-e0164538
Hauptverfasser:	Li, Li, Zhang, Jiangyu, Deng, Qingshan, Li, Jieming, Li, Zhengfen, Xiao, Yao, Hu, Shuiwang, Li, Tiantian, Tan, Qiuxiao, Li, Xiaofang, Luo, Bingshu, Mo, Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis Biological markers Biology and Life Sciences Biomarkers Biomarkers - metabolism Biopsy Blotting, Western Calcium binding proteins Calcium-binding protein Calmodulin Diabetes Disease Drug development Female Gel electrophoresis Gynecology Heat shock proteins Hospitals Humans Immunohistochemistry Insulin resistance Kinases Laboratories Mass spectrometry Mass spectroscopy Medical research Medicine and Health Sciences Menstruation Metabolism Muscle proteins Obstetrics Ovaries Ovary - metabolism Pathogenesis Phosphorylation Polycystic ovary syndrome Polycystic Ovary Syndrome - metabolism Progesterone Protein binding Proteins Proteomics Proteomics - methods Research and Analysis Methods Retinoids Retinol-binding protein Retinol-binding protein 1 Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Spectroscopy Systematic review Tissues Tropomyosin Tumors Type 2 diabetes Vitamin A Womens health Young Adult
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