High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations

High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, given the well-known and widespread phenomenon of g...

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Veröffentlicht in:PLoS genetics 2016-10, Vol.12 (10), p.e1006339-e1006339
Hauptverfasser: Payen, Celia, Sunshine, Anna B, Ong, Giang T, Pogachar, Jamie L, Zhao, Wei, Dunham, Maitreya J
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Sprache:eng
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