Retrospective Analysis of Serotype Switching of Vibrio cholerae O1 in a Cholera Endemic Region Shows It Is a Non-random Process

Genomic data generated from clinical Vibrio cholerae O1 isolates collected over a five year period in an area of Kolkata, India with seasonal cholera outbreaks allowed a detailed genetic analysis of serotype switching that occurred from Ogawa to Inaba and back to Ogawa. The change from Ogawa to Inab...

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Veröffentlicht in:	PLoS neglected tropical diseases 2016-10, Vol.10 (10), p.e0005044
Hauptverfasser:	Karlsson, Stefan L, Thomson, Nicholas, Mutreja, Ankur, Connor, Thomas, Sur, Dipika, Ali, Mohammad, Clemens, John, Dougan, Gordon, Holmgren, Jan, Lebens, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	africa Biology and Life Sciences Cholera - epidemiology Cholera - microbiology controlled-trial Disease Outbreaks efficacy el-tor Endemic Diseases Epidemics Genes Genetic aspects Genetic testing Genome, Bacterial Humans Immunologi inom det medicinska området Immunology in the medical area inaba india India - epidemiology Infectious Diseases Infectious Medicine Infektionsmedicin Medicine and Health Sciences Methyltransferases - genetics Microbiology in the medical area Mikrobiologi inom det medicinska området Mutation O Antigens - chemistry O Antigens - genetics outbreaks Pandemics Parasitology Phylogeny Physical Sciences Physiological aspects Retrospective Studies Sequence Analysis, DNA Serogroup Serotyping transmission Tropical diseases Tropical Medicine vaccine Vaccines Vibrio cholerae Vibrio cholerae O1 - classification Vibrio cholerae O1 - genetics Vibrio cholerae O1 - immunology Vibrio cholerae O1 - isolation & purification Waterborne diseases
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