FTO Gene Polymorphism Is Associated with Type 2 Diabetes through Its Effect on Increasing the Maximum BMI in Japanese Men

Several studies have demonstrated that polymorphisms within the fat-mass and obesity-associated gene (FTO) are associated with type 2 diabetes (T2D). However, whether the effects of the FTO locus on T2D susceptibility are independent of fat-mass increases remains controversial. To investigate this i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2016-11, Vol.11 (11), p.e0165523-e0165523
Hauptverfasser:	Kamura, Yutaka, Iwata, Minoru, Maeda, Shiro, Shinmura, Satomi, Koshimizu, Yukiko, Honoki, Hisae, Fukuda, Kazuhito, Ishiki, Manabu, Usui, Isao, Fukushima, Yasuo, Takano, Atsuko, Kato, Hiromi, Murakami, Shihou, Higuchi, Kiyohiro, Kobashi, Chikaaki, Tobe, Kazuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Aged Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics Analysis Asian Continental Ancestry Group - genetics Biology and Life Sciences Body mass Body Mass Index Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - genetics Diagnosis Endocrinology Female Fto gene Gene Frequency Gene polymorphism Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease - genetics Hospitals Humans Internal medicine Japan Laboratories Male Medicine Medicine and Health Sciences Men Metabolism Middle Aged Obesity Physical Sciences Polymorphism Polymorphism, Single Nucleotide Research and Analysis Methods Sex Single-nucleotide polymorphism Studies Type 2 diabetes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!